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MetabolomicsEcophysiological Study of Paraburkholderia sp. Strain 1N under Soil Solution Conditions: Dynamic Substrate Preferences and Characterization of Carbon Use Efficiency

We used time-resolved metabolic footprinting, an important technical approach used to monitor changes in extracellular compound concentrations during microbial growth, to study the order of substrate utilization (i.e., substrate preferences) and kinetics of a fast-growing soil isolate, Parabu...

2020-09-28 | MTBLS1692 | MetaboLights
TranscriptomicsPrp8 Retinitis Pigmentosa Mutants Cause Defects in the Transition between the Catalytic Steps of Splicing
The essential process of pre-mRNA splicing must occur with high fidelity and efficiency for proper gene expression. The spliceosome employs DExD/H box helicases to promote on-pathway interactions while simultaneously minimizing errors. Prp8 and Snu114, an EF2-like GTPase, regulate the activity of th...
ORGANISM(S): Saccharomyces cerevisiae 
2016-07-21 | E-GEOD-75081 | biostudies-arrayexpress
GenomicsDirected evolution improves the catalytic efficiency of APEX2-mediated proximity-dependent RNA labeling
Directed evolution improves the catalytic efficiency of APEX2-mediated proximity-dependent RNA labeling
PRJNA1090511 | ENA
TranscriptomicsTranscription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-15082 | biostudies-arrayexpress
GenomicsThe catalytic efficiency of METTL16 affects cellular methyltransferase activities by governing the intracellular S-adenosylmethionine setpoint
The catalytic efficiency of METTL16 affects cellular methyltransferase activities by governing the intracellular S-adenosylmethionine setpoint
PRJNA1258953 | ENA
TranscriptomicsDirected evolution improves the catalytic efficiency of APEX2-mediated proximity-dependent RNA labeling
Engineered ascorbate peroxidase APEX2 has seen widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin-aniline (Btn-An) remains suboptimal. To overcome this limitation, we performed yeast surface display ba...
ORGANISM(S): Homo sapiens 
2026-03-26 | GSE262170 | GEO
UnknownSupramolecular Peptide Nanostructures Regulate Catalytic Efficiency and Selectivity.
Not available
S-EPMC10330506 | biostudies-literature
UnknownEnhanced catalytic efficiency of CotA-laccase by DNA shuffling.
Not available
S-EPMC6550543 | biostudies-literature
TranscriptomicsEM-seq of TET1 knockout, catalytic mutant and wild type mESCs
Investigation of TET1 non-catalytic functions in mESCs cultured in serum + LIF (primed) on DNA methylation
ORGANISM(S): Mus musculus 
2022-08-01 | E-MTAB-10933 | biostudies-arrayexpress
UnknownEnhancing catalytic efficiency of Bacillus subtilis laccase BsCotA through active site pocket design.
Not available
S-EPMC11377520 | biostudies-literature
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