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GenomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Cut&Tag
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modelled this leukemic evolution through ...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-11032 | biostudies-arrayexpress
TranscriptomicsATACseq : role of trisomy 21, GATAs mutation and associated mutations in the development of trisomy 21
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modelled this leukemic evolution through ...
ORGANISM(S): Homo sapiens 
2022-06-15 | E-MTAB-11044 | biostudies-arrayexpress
TranscriptomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Single cell RNAseq
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modelled this leukemic evolution through ...
ORGANISM(S): Homo sapiens 
2022-09-29 | E-MTAB-11036 | biostudies-arrayexpress
TranscriptomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: RNAseq
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modeled this leukemic evolution through s...
ORGANISM(S): Homo sapiens 
2022-09-29 | E-MTAB-11033 | biostudies-arrayexpress
TranscriptomicsRNA-seq of RBC depleted whole blood from COVID-19 patients and controls
Red blood cells (RBC) depleted whole blood from COVID-19 patients and controls was harvested and processed in order to performed 10X single cell RNA-seq. For COVID-19 patients 2 samples 10 days a part were analyzed.
ORGANISM(S): Homo sapiens 
2020-08-21 | E-MTAB-9221 | biostudies-arrayexpress
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