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ProteomicsProteomic analysis of vastus lateralis muscle biopsies
The molecular level the different muscular signature from Veteran soccer Players (VPG) vs age-matched active healthy subjects (control group, CG) was explored by using a proteomic approach. V. lateralis muscle biopsies were investigated in order to highlight the molecular mechanisms that characteriz...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037792 | Pride
Human proteomics Muscle biopsy 
MetabolomicsDysregulation of lipid metabolism and pathological inflammation in patients with COVID-19
In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 patients show mild, moderate or severe symptoms with the latter ones requiring access to specialized intensive care. SARS-CoV-2 infec...
2023-02-01 | MTBLS6844 | MetaboLights
ProteomicsLabel free proteomic analysis of CAL62/miR-331-5p cells
The ectopic expression of miR-331-5p suppresses TC cell (CAL62 and TPC-1) malignant behavior was demonstrate
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039884 | Pride
Human proteomics 
ProteomicsNew label free methods for protein relative quantification applied to the investigation of animal model of Huntington Disease.
Spectral Counts approaches (SpCs) are largely employed for the comparison of protein expression profiles in label free differential proteomics applications. Similarly, to other comparative methods, also SpCs based approaches require a normalization procedure before Fold Changes (FC) calculation. Her...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-18 | PXD017471 | Pride
Label free methods  spectral counts normalization  complexity-based correction factor  huntington disease mice models 
ProteomicsAnalysis of the interactome of RPS19 mutants
Ribosomal protein S19 (RPS19) is a 16-kDa protein found mainly as a component of the ribosomal 40 S subunit. Its mutations are responsible for Diamond Blackfan anemia, a congenital disease characterized by defective erythroid progenitor maturation. To clarify the function of RPS19, we compare the in...
ORGANISM(S): Homo sapiens (Human) 
2014-08-11 | PXD000640 | Pride
Diamond-blackfan anemia  protein-protein interaction in ribosome 
ProteomicsStandardization of mitochondrial proteomics
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-30 | MSV000081121 | MassIVE
ProteomicsStandardization of mitochondrial proteomics v2 NP
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-14 | MSV000081329 | MassIVE
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