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TranscriptomicsTreatment of human monocyte-derived dendritic cells with Saccaromyces cerevisiae in exponential growth phase
In vitro experiment of stimulation of monocyte-derived dendritic cells with Saccaromyces cerevisiae in exponential growth phase. This experiment was performed to verify the comparability of microarray experiments using a pathway based logic (Beltrame et al., PLoS 2009) by comparing the analysis of t...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-13901 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of the effects of 089 on a panel of yeast strains
The analysis allow to delve into the molecular activity of the molecule 089, wich induced a growth decrease on various yeast strains. Yeast strains selected are knock-out mutants in genes involved in MDR (BY4742Δerg6, BY4742Δsnq2) and the parental strain (BY4742). Six samples analyzed, two biologi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-19331 | biostudies-arrayexpress
TranscriptomicsGrowth competition experiment on the Yeast Homozygous Diploid Deletion Pool to investigate which ORFs conferred an advantage/disadvantage when growing on both standard and high concentration of oleic acid
The combination of genetic analysis and genome-wide expression profiles make Saccharomyces cerevisiae the cradle of Systems Biology. The way S. cerevisiae uses carbon sources has long been a landmark for studies concerning cellular responses to environmental conditions. S. cerevisiae conserves the e...
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-25 | E-GEOD-21620 | biostudies-arrayexpress
MetabolomicsCore Microbiota and Metabolome of Vitis vinifera L. cv. Corvina Grapes and Musts

The composition and changes of the fungal population and of the metabolites present in grapes and in ferments of Vitis vinifera L. cv. Corvina, one of the major components of the Amarone musts, were dissected aiming at the identification of constant characteristics possibly influenced by the prod...

2017-11-14 | MTBLS392 | MetaboLights
TranscriptomicsRNA-Seq of healthy human dendritic cells after challenge with four different fungal pathogens, and of four fungal pathogens after challenge with healthy human dendritic cells, SYBARIS project.
Dendritic cells from three healthy human donors were cultured in the presence or absence of either Aspergillus fumigatus, Saccharomyces cerevisiae, Candida albicans or Candida parapsilosis. Each of the four fungi were also cultured in the absence of human cells. RNA-sequencing was used to evaluate d...
ORGANISM(S): Homo sapiens + Candida albicans 
2016-04-30 | E-SYBR-2 | biostudies-arrayexpress
TranscriptomicsIn vitro transcriptional profiling of dendritic cells treated with Denileukin diftitox (ONTAK)
In order to assess the transcriptional modifications of dendritic cells treated with Denileukin diftitox (ONTAK), we profiled the whole transcriptome of monocyte-derived dendritic cells (moDC) from blood of healthy volounteers after stimulation with a maturation cocktail with or without the addition...
ORGANISM(S): Homo sapiens 
2013-09-04 | E-MTAB-979 | biostudies-arrayexpress
TranscriptomicsTreatment of dendritic cells and monocytes from immunotherapy treated patients with ONTAK
In this experiment, dendritic cells and monocytes obtained from melanoma patients who underwent immunotherapy were stimulated with a maturation cocktail then either treated or not treated with denlieukin diftitox (DD; ONTAK) and then subjected to transcription profiling to investigate the effects of...
ORGANISM(S): Homo sapiens 
2013-09-04 | E-MTAB-977 | biostudies-arrayexpress
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