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TranscriptomicsHepG2 cells exposed to pesticides and related compounds
HepG2 cells were exposed for 24 hours to the IC20 (72hr MTT) dose of various pesticides and related compounds selected from the EPA Toxcast phase 1 set. This is the first part of two batches of experiments, these experiments were used as a training set and the second batch as a validation set.
ORGANISM(S): Homo sapiens 
2019-06-20 | E-MTAB-3508 | biostudies-arrayexpress
TranscriptomicsHepG2 cells exposed to pesticides and related compounds (part 2)
HepG2 cells were exposed for 24 hours to the IC20 (72hr MTT) dose of various pesticides and related compounds selected from the EPA Toxcast phase 1 set. This is the first part of two batches of experiments, these experiments were used as a validation set and the first batch as a training set.
ORGANISM(S): Homo sapiens 
2019-06-20 | E-MTAB-3509 | biostudies-arrayexpress
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (miRNA)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63559 | biostudies-arrayexpress
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