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GenomicsGenome-wide map of HBO1 in cancer derived human cell line
We used ChIP-seq technology in order to map chromatin binding sites of the HBO1 MYST complex in the RKO cell line. We obtained a significant enrichment of the HBO1 signal right after TSS regions of genes and also In the proximal promoter region, with no signal on TSS. This enrichment also correlates...
ORGANISM(S): Homo sapiens 
2012-03-15 | E-GEOD-33007 | biostudies-arrayexpress
TranscriptomicsEffects of the JADE-HBO1 complex on gene expression
We find that 499 genes are up-regulated and 457 are down-regulated in response to over-expression of JADE1, while 397 genes are up-regulated and 385 are down-regulated after HBO1 knock-down. For each condition - HBO1 siRNA treatment or JADE1 over-expression - two biological replicates were analyzed ...
ORGANISM(S): Homo sapiens 
2012-03-15 | E-GEOD-33220 | biostudies-arrayexpress
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