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GenomicsCcp1 homodimer mediates chromatin integrity by antagonizing CENP-A loading
CENP-A is a centromere-specific histone 3 variant essential for centromere specification. CENP-A partially replaces canonical histone H3 at the centromeres. How the particular CENP-A/H3 ratio at centromeres is precisely maintained is unknown. It also remains unclear how CENP-A is excluded from non-c...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-04 | E-GEOD-85166 | biostudies-arrayexpress
GenomicsMigrating interneuron transcriptomes in Wt and CCP1 cKO mouse embryos
Migrating interneuron transcriptomes in Wt and CCP1 cKO mouse embryos
PRJNA408229 | ENA
GenomicsGenome-wide mapping of Ccp1 association sites in fission yeast
In our genetic screen, we found that Ccp1 is an epigenetic stability modulator in centromeres and heterochromatin in S. pombe. In interphase cells,Ccp1-GFP enriched at centromeres. To determine the association sites of Ccp1 with the centromeres and to characterize the global distribution pattern of ...
ORGANISM(S): Schizosaccharomyces pombe 
2018-06-13 | GSE95046 | GEO
TranscriptomicsMigrating interneuron transcriptomes in Wt and CCP1 cKO mouse embryos
CCP1 is a deglutamylase responsible for protranslational modification of proteins. CCP1 cKO interneurons show impaired acto-myosin contraction and increased invasion of the cortex. Transcriptome analysis of Wt and cKO interneurones aimes at uncovering secondary disregulation of gene expression.
ORGANISM(S): Mus musculus 
2018-02-22 | GSE104090 | GEO
GenomicsCcp1 homodimer mediates chromatin integrity by antagonizing CENP-A loading
CENP-A is a centromere-specific histone 3 variant essential for centromere specification. CENP-A partially replaces canonical histone H3 at the centromeres. How the particular CENP-A/H3 ratio at centromeres is precisely maintained is unknown. It also remains unclear how CENP-A is excluded from non-c...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-04 | GSE85166 | GEO
UnknownCcp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading.
Not available
S-EPMC5055466 | biostudies-literature
UnknownLoss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration.
Not available
S-EPMC6276871 | biostudies-literature
GenomicsSchizosaccharomyces pombe
Genome-wide mapping of Ccp1 association sites in fission yeast
PRJNA375809 | ENA
UnknownCcp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly.
Not available
S-EPMC8640933 | biostudies-literature
UnknownCCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development.
Not available
S-EPMC10049023 | biostudies-literature
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