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By characterizing physiological changes that occur in warfighters during simulated combat, we can start to unravel the key biomolecular components that are linked to physical and cognitive performance. Viable field-based sensors for the warfighter must be rapid and noninvasive. In an effort to facil...
2023-12-05 | MTBLS5463 | MetaboLights
Plant growth is severely affected by toxic concentrations of the non-essential heavy metal cadmium (Cd). Comprehensive transcriptome analysis by RNA-Seq following cadmium exposure is required to further understand plant responses to Cd and facilitate future systems-based analyses of the underlying r...
ORGANISM(S): Oryza sativa Japonica Group 
To massively identify genes that are up-regulated by Cd and in particular transporter genes which might transport peptides or oligopeptides. Four week old hydroponically-grown Col-0 plants were treated with/without 200uM Cd for 6 hours. Total RNA was extracted from roots and subjected to hybridizat...
ORGANISM(S): Arabidopsis thaliana 

Desalination brine discharge poses emerging threats to benthic marine organisms through combined salinity stress and metal contamination. This study investigated the individual and combined effects of salinity (35 ppt) and metal exposure (Cu, Fe, and Cd) on the sea cucumber Apostichopus japonicus...

2026-03-18 | MTBLS14079 | MetaboLights
We showed earlier that nutritional stress like starvation or high fat diet resulted in phenotypic changes in the lipidomes of hepatocyte lipid droplets (LDs), representative for the pathophysiological status of the mouse model. Here we extend our former study by adding genetic stress due to knock-ou...
2014-08-19 | MTBLS81 | MetaboLights
Several metals are essential nutrients for plants but metals are toxic in excess, deleteriously affecting crop yield and quality. Various kinds of genes involved in metal homeostasis have been investigated in detail over the past few decades and the mechanisms of how metals are absorbed from soil an...
ORGANISM(S): Oryza sativa 
RNA illumina sequencing of Panax notoginseng under CK and Cd stress treatment

Cadmium (Cd) poses a serious threat to plant growth, so the selection and breeding of Cd-tolerant pepper cultivars is an effective method to reduce Cd hazards. This study identified C. annuum G03 as a Cd-tolerant cultivar, evidenced by its superior leaf physiological activity under Cd stress comp...

2025-10-23 | MTBLS13200 | MetaboLights
Engineered abiotic stress resistance is an important target for increasing agricultural productivity.There are concerns, however, regarding possible ecological impacts of transgenic crops. In contrast to the first wave of transgenic crops, many abiotic stress resistance genes can initiate complex do...
ORGANISM(S): Arabidopsis thaliana 

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed tha...

2022-09-22 | MTBLS2744 | MetaboLights
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