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TranscriptomicsSuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset
Monocytes are a heterogeneous cell population with subset-specific functions and phenotypes. The differential expression of CD14 and CD16 distinguishes classical CD14++CD16-, intermediate CD14++CD16+ and non-classical CD14+CD16++ monocytes. However, CD14++CD16+ monocytes remain the most poorly chara...
ORGANISM(S): Homo sapiens 
2011-07-24 | E-GEOD-30811 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD16+ and CD16- peripheral blood monocytes from healthy individuals
Human peripheral blood monocytes (Mo) consist of subsets distinguished by expression of CD16 (FCGRIII) and chemokine receptors. Classical CD16- Mo express CCR2 and migrate in response to CCL2, while a minor CD16+ Mo subset expresses CX3CR1 and migrates into tissues expressing CX3CL1. CD16+ Mo produc...
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-16836 | biostudies-arrayexpress
GenomicsChIP-seq mapping of histone modifications in CD14++ CD16- monocytes from human blood samples
Chromatin immunoprecipitation in combination with a genome-wide analysis via high-throughput sequencing is the state of the art method to gain genome-wide representation of histone modification or transcription factor binding profiles. However, chromatin immunoprecipitation analysis in the context o...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-54634 | biostudies-arrayexpress
GenomicsGene expression in CD14+ and CD16+ monocytes
Gene expression in CD14+ and CD16+ monocytes
PRJNA776172 | ENA
TranscriptomicsGene expression analysis of gamma-M.tuberculosis-stimulated CD14hiCD16- and CD14loCD16+ monocytes
Current study will help us to elucidate the differential gene expression profiles of two different subsets of monocytes stimulated with gamma-M. tuberculosis CD14hiCD16- and CD14loCD16+ monocytes were isolated from human peripheral blood using magnetic beads for CD14 and CD16. 1.5 million cells were...
ORGANISM(S): Homo sapiens 
2010-11-23 | E-GEOD-25505 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD14+ CD16- and CD14low CD16+ monocytes from patients with Sjogrens syndrome and normal controls
Sjogren's syndrome is an autoimmune disease, characterized by complaints such as xerostomia and keratoconjunctivitis sicca. In other autoimmune diseases such as diabetes and SLE, monocyte abberancies have been described. Therefore, this study aimed at studying the monocyte compartment in Sjogren's S...
ORGANISM(S): Homo sapiens 
2008-08-04 | E-MEXP-1242 | biostudies-arrayexpress
TranscriptomicsHuman CD14+CD16- and CD16+ monocyte-derived macrophages primed by GM-CSF or M-CSF
Identification of genes differentially expressed between human CD14+CD16- and CD16+ monocyte-derived macrophages generated in the presence of either GM-CSF (termed GM14 and GM16, respectively) or M-CSF (termed M14 and M16, respectively) Human peripheral CD14+CD16- and CD16+ blood monocytes from thr...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-68061 | biostudies-arrayexpress
GenomicsDistinct constitutive and pathogen-induced transcriptional programs in dendritic cells derived from CD16- versus CD16+ monocytes
Distinct constitutive and pathogen-induced transcriptional programs in dendritic cells derived from CD16- versus CD16+ monocytes
PRJNA437144 | ENA
TranscriptomicsGene expression profiling of the classical (CD14++CD16-), intermediate (CD14++CD16+) and nonclassical (CD14+CD16+) human monocyte subsets
The new official nomenclature subdivides human monocytes into three subsets, classical (CD14++CD16-), intermediate (CD14++CD16+) and nonclassical (CD14+CD16+). Here, we comprehensively define relationships and unique characteristics of the three human monocyte subsets using microarray and flow cytom...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-25913 | biostudies-arrayexpress
GenomicsCD16+ CD163+ monocytes traffic to sites of inflammation in NEC
CD16+ CD163+ monocytes traffic to sites of inflammation in NEC
PRJNA737360 | ENA
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