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Male fertility and testis function changes with age and so it was sought to determine if these changes are accompanied by changes in gene expression in the spermatogonial cells at the foundation of spermatogenesis A full genome microarray was used to determine if distinct pathways of genes were alte...
ORGANISM(S): Rattus norvegicus 
Clostridioides difficile CD9 Genome sequencing and assembly
In the following experiment, three different hESC cell lines (HES2, MEL1 and H9) were grown in the presence of KOSR, KOSR or mTESR containing media respectively. KOSR (Knockout serum replacement medium) is a standard media allowing the growth of hESC without the need for manual passaging - Enzymatic...
ORGANISM(S): Homo sapiens 
Epithelial colonisation is often a critical first step in bacterial pathogenesis, however, different bacterial species utilise several different receptors at the cell membrane interface to adhere to cells. We have previously demonstrated that interference of the human tetraspanin, CD9, can reduce ad...
ORGANISM(S): Homo sapiens (Human) Staphylococcus aureus subsp. aureus NCTC 8325 Neisseria meningitidis serogroup B (strain MC58) 
2025-10-28 | PXD058283 | Pride
We developed a column-based CD9 antibody-immobilized HPLC immunoaffinity (CD9-HPLC-IAC) technology for EV isolation from a microliter-scale of serum for downstream proteomic analysis. The CD9-HPLC-IAC method achieved EV isolation from 40 μL of serum in 30 min with a yield of 8.0×109 EVs. Proteomic a...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD027025 | Pride
Vascular smooth muscle cell (VSMC) migration and proliferation are critical events in the development of neointima following vascular injury. Exogenous expression of human CD9 by CD9-adenoviral transduction led to increases in neointima. CD9 expression significantly augmented PI-3 kinase dependen...
ORGANISM(S): Rattus norvegicus 
Bortezomib therapy has been proven successful for the treatment of relapsed and/or refractory multiple myeloma (MM). However, both intrinsic and acquired resistance has already been observed. In this study, we explored the relationship between CD9 expression and bortezomib sensitivity in MM Both int...
ORGANISM(S): Homo sapiens 
HES2 ESCs were grown in standard ES culture conditions. After 1 week, these cells were FACs sorted for the presence of GCTM-2 and CD9. Keywords: Sorted cell comparison Three consecutive passages of HES2 cells were grown and subjected to FACs sorting. For each, 4 sorted populations of cells (p4, p5...
ORGANISM(S): Homo sapiens 
The placenta serves as the structural interface for nutrient and waste exchange for proper fetal development. Although defects in placental function result in various placental disorders, molecular mechanisms orchestrating placental development and function are poorly understood. Gene targeting stud...
ORGANISM(S): Mus musculus 
Epithelial colonisation is often a critical first step in bacterial pathogenesis, however, different bacterial species utilise several different receptors at the cell membrane interface to adhere to cells. We have previously demonstrated that interference of the human tetraspanin, CD9, can reduce ad...
ORGANISM(S): Neisseria meningitidis serogroup B Homo sapiens (Human) Staphylococcus aureus 
2025-10-28 | PXD067302 | Pride
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