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Effects of CDC5L knockdown on gene transcription levels in HeLa cell lines
Discovery of genes directly bound to CDC5L in HeLa cell lines [ChIP]
Effects of CDC5L knockdown on gene transcription levels in HeLa cell lines [RNA]
Stress granules (SGs) are membraneless condensates that assemble in response to cellular stress. We identified cell division cycle 5-like protein (CDC5L) as a regulator of SG dynamics, where CDC5L knockdown triggered SG formation even in the absence of exogenous stress. Reduced CDC5L levels led to u...
ORGANISM(S): Homo sapiens 
2026-07-20 | GSE306238 | GEO
We identified the gene cell division cycle 5-like protein (CDC5L), whose knockdown induced SG formation in the absence of any cellular stress. Moreover, lower protein levels of CDC5L increased mRNA and protein levels of PERK. Through ChIP-PCR, we found that CDC5L regulated transcription by directly ...
ORGANISM(S): Homo sapiens 
2026-07-20 | GSE242278 | GEO
Oncogenic properties of NEAT1 in prostate cancer cells depend on the CDC5L-AGRN transcriptional regulation circuit
Stress granules (SGs) are membraneless protein condensates that form in the cytoplasm of a cell upon exposure to cellular stressors. Here, we identified the gene cell division cycle 5-like protein (CDC5L), whose knockdown induced SG formation in the absence of any cellular stress. Moreover, lower pr...
ORGANISM(S): Homo sapiens 
2026-07-20 | GSE242279 | GEO
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