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Transcriptome of CDKN1C-siRNA-injected embryos were compared to sham-injected embryos using RNA-sequencing to determine the genes and pathways downstream of the silenced gene that may have been altered. Transcriptome comparison between two pools of embryos (i.e. CDKN1C-siRNA-injected vs sham-injecte...
ORGANISM(S): Bos taurus 
Imprinted Cdkn1c Genomic Locus Cell-Autonomously Promotes Cell Survival in Cerebral Cortex Development
Expression data from cultured spermatogonia established from Cdkn1c conditional knockout mouse testes
Imprinted Cdkn1c Genomic Locus Cell-Autonomously Promotes Cell Survival in Cerebral Cortex Development [cdkn1c_KO]
Imprinted Cdkn1c Genomic Locus Cell-Autonomously Promotes Cell Survival in Cerebral Cortex Development [Cdkn1c_allelic expression]
Mice lacking Cdkn1c (p57) in spermatogonia were found to be congenitally infertile due to spermatogonia depletion. Transplantation experiments showed that Cdkn1c deficiency compromised spermatogonial stem cells (SSC) activity. SSCs undergo self-renewal division to sustain spermatogenesis, and it is ...
ORGANISM(S): Mus musculus 
2025-01-30 | GSE253319 | GEO
The cyclin-dependent kinase inhibitor p57KIP2 is encoded by the imprinted Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex development. How Cdkn1c regulates corticogenesis is however not clear. To this end we employ Mosaic Analysis with Double Markers (MADM) technolog...
ORGANISM(S): Mus musculus 
2020-01-21 | GSE138227 | GEO
The cyclin-dependent kinase inhibitor p57KIP2 is encoded by the imprinted Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex development. How Cdkn1c regulates corticogenesis is however not clear. To this end we employ Mosaic Analysis with Double Markers (MADM) technolog...
ORGANISM(S): Mus musculus 
2020-01-21 | GSE138228 | GEO
The cyclin-dependent kinase inhibitor p57KIP2 is encoded by the imprinted Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex development. How Cdkn1c regulates corticogenesis is however not clear. To this end we employ Mosaic Analysis with Double Markers (MADM) technolog...
ORGANISM(S): Mus musculus 
2019-12-03 | GSE138229 | GEO
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