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GenomicsCDO1 is a new biomarker to discriminate aggressive forms of prostate cancer
CDO1 is a new biomarker to discriminate aggressive forms of prostate cancer
PRJNA1445860 | ENA
TranscriptomicsExercise-induced renal tubular Cdo1 protects against diabetic nephropathy
Exercise is an effective intervention for diabetic nephropathy (DN), but its molecular mechanisms remain incompletely understood. Here, we identify cysteine dioxygenase type 1 (Cdo1) as a mediator of exercise-induced renal protection. Exercise upregulates renal tubular Cdo1 expression via the α-keto...
ORGANISM(S): Mus musculus 
2026-06-09 | GSE334164 | GEO
GenomicsCdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice
PRJNA1000631 | ENA
TranscriptomicsRNA-seq of CDO1-overexpressing AGS gastric cancer cells
This study investigates transcriptomic changes associated with CDO1 overexpression in human AGS gastric cancer cells. Poly(A)-selected mRNA libraries from CDO1-overexpressing AGS cells and corresponding control cells were sequenced using paired-end 150-bp reads on the DNBSEQ-T7 platform to identify ...
ORGANISM(S): Homo sapiens 
2026-07-25 | GSE339180 | GEO
TranscriptomicsCdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice
Cysteine dioxygenase type 1 (Cdo1) is a key enzyme for cysteine catabolism that is enriched in liver, whose role in NAFLD remains poorly understood. Here, we show that exercise induces the expression of hepatic Cdo1 via the cAMP/PKA/CREB signaling pathway. Hepatocyte-specific knockout of Cdo1 (Cdo1L...
ORGANISM(S): Mus musculus 
2023-08-07 | GSE239729 | GEO
TranscriptomicsCDO1 is a new biomarker to discriminate aggressive forms of prostate cancer
Worldwide, prostate cancer (PCa) ranks second in terms of incidence and eighth in terms of mortality. While most cancers remain silent after initial treatment, some tumors recur. At present, we are unable to predict which patients are at risk of recurrence. In order to determine this risk of recurre...
ORGANISM(S): Homo sapiens 
2026-07-15 | GSE326541 | GEO
GenomicsCysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1
Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1
PRJNA1364011 | ENA
UnknownDetection of methylated CDO1 in plasma of colorectal cancer; a PCR study.
Not available
S-EPMC4254285 | biostudies-literature
TranscriptomicsCysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1
Regulation of metabolic enzymes through degradation by the ubiquitin-proteosome system regulation is essential towards maintenance of cellular homeostasis. Our approach directly addresses a problem in the field; linking metabolic signal to an E3 ligase response. We employ active E3 ligase profiling ...
ORGANISM(S): Homo sapiens 
2026-04-17 | GSE309930 | GEO
UnknownCDO1 phosphorylation is required for IL-6-induced tumor cell proliferation through governing cysteine availability.
Not available
S-EPMC12016070 | biostudies-literature
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