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TranscriptomicsGene expression profiling of conditional ablation of Indian hedgehog in the mouse uterus
Conditional ablation of Indian hedgehog (Ihh) in the murine uterus results in mice that are sterile due to defects in embryo implantation. We performed microarray analysis on these mice at the time point at which the Ihh target genes are induced by the administration of exogenous hormone to mimic d...
ORGANISM(S): Mus musculus 
2010-03-06 | E-GEOD-19517 | biostudies-arrayexpress
TranscriptomicsThe effects of LH ablation/replacement versus steroid ablation/replacement on gene expression in primate corpora lutea
This study was designed to provide a genome-wide analysis of the effects of luteinizing hormone (LH) ablation/replacement versus steroid ablation/replacement on gene expression in the developed corpus luteum (CL) in primates during the menstrual cycle. Naturally cycling, female rhesus monkeys were l...
ORGANISM(S): Macaca mulatta 
2009-01-25 | E-GEOD-12281 | biostudies-arrayexpress
MetabolomicsHuman basal cell carcinoma samples analysed by laser desorption rapid evaporative ionisation mass spectrometry (LD-REIMS) imaging

Laser ablation rapid evaporative ionisation mass spectrometry (LA-REIMS) was used to analyse human basal cell carcinoma (BCC) samples. 14 samples are presented here, along with H&E-stained histological images.

2025-07-28 | MTBLS12786 | MetaboLights
TranscriptomicsComparison of microRNA expression after AF-Ablation with Cryo balloon vs. Pulsed field ablation
Human citrate Plasma was collected from the left atrial appendage directly after catheter ablation for atrial fibrillation with either teh Boston Scientific Cryo-Balloon System or the Boston Scientific Pulsed Field Ablation System. A total of 154 microRNAs (miRs) were consistently detected across a...
ORGANISM(S): Homo sapiens 
2025-12-31 | E-MTAB-14837 | biostudies-arrayexpress
TranscriptomicsNFATc1 controls the survival, function and suppressive capacity of B lymphocytes upon B cell receptor stimulation
Triggering of B cell receptors (BCR) induces a massive synthesis of NFATc1 in splenic B cells. By inactivating the Nfatc1 gene and re-expressing NFATc1 we show that NFATc1 levels are critical for the survival of splenic B cells upon BCR stimulation. NFATc1 ablation led to decreased BCR-induced Ca++ ...
ORGANISM(S): Mus musculus 
2011-03-23 | E-GEOD-21063 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of murine GIST-like tumors after Etv1 ablation
We used a mouse expressing three alleles 1) KitV558Delta/+ activating allele that develop GIST-like tumors in the cecum, 2) Etv1 flox/flox conditional knockout allele and 3) Rosa26-CreERT2 tamoxifen activated Cre allele. Mice were treated with either Tamoxifen (to delete Etv1) or corn oil (control)....
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-64608 | biostudies-arrayexpress
ProteomicsDirect 3D sampling of the embryonic mouse head: Layer-wise nanosecond infrared laser (NIRL) ablation from scalp to cortex for spatially resolved proteomics
Common workflows in bottom-up proteomics require homogenization of tissue samples giving to get access to the biomole-cules within the cells. The homogenized tissue samples often contain many different cell types, thereby representing an average of the natural proteome composition and rare cell type...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD043011 | Pride
Nirl ablation Spatial proteomics Tissue sampling Bottom-up proteomics 
TranscriptomicsEffects of eyestalk ablation on the gene expression levels in female black tiger shrimp broodstock (Penaeus monodon)
Comparisons of gene expression profiles between ovaries of before (day 0) and after eyestalk ablation (days 1, 4 and 7) of domesticated 14-month-old black tiger shrimp (Penaeus monodon) were made using a cDNA microarray. Differentially expressed genes were identified through the microarray analysis...
ORGANISM(S): Penaeus monodon 
2012-05-01 | E-GEOD-29025 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of unstressed and pressure-overloaded C57 mouse hearts with single or combined ablation of PKCdelta and PKCepsilon
Combinatorial ablation of the major cardiac-expressed novel protein kinase C isoforms, PKCdelta and PKCepsilon, in murine cadiac myocytes unmasked functionally redundant growth-limiting effects of these kinases in hemodynamically stressed adult hearts and during normal embryonic cardiac development,...
ORGANISM(S): Mus musculus 
2015-04-21 | E-GEOD-62689 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of maize anthers using genetic ablation to analyze pre-meiotic and tapetal cell types
Agilent oligonucleotide arrays were used to profile gene expression in dissected maize anthers of 3 types of male-sterile plants and their fertile siblings at four stages of development: after anther initiation, at the rapid mitotic proliferation stage, pre-meiosis, and meiotic prophase I. The male...
ORGANISM(S): Zea mays 
2008-09-16 | E-GEOD-12756 | biostudies-arrayexpress
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