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Actomyosin contractility regulates cell morphology and movement. The objective of this study was to identify whether actomyosin contractility regulates gene expression in tumour cells and whether such genes are involved in cell morphology and movement. Gene expression analysis was carried out on h...
ORGANISM(S): Homo sapiens 
Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction, and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the mol...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2024-09-19 | PXD052350 | Pride
Cell contractility drives mechanical memory of oral squamous cell carcinoma
CDK4 maintains cytoskeletal homeostasis by restraining actomyosin contractility
CELL CONTRACTILITY AND AN ACTIN GRADIENT DRIVE POLAR ALIGNMENT OF FIBROBLASTS IN CONSTRAINED GEOMETRIES
MASTL (Microtubule associated serine-threonine kinase-like) is a relatively recently identified mitotic accelerator. There are also indications of its role in cancer progression, especially in breast cancer, but the molecular mechanisms behind this and the cell cycle independent functions of MASTL a...
ORGANISM(S): Homo sapiens (Human) 
2020-04-14 | PXD013757 | Pride
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