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GenomicsIntegrative epigenomic analysis in MLL-AF9 acute myeloid leukemia (AML) and B-acute lymphoblastic leukemia (B-ALL)
Next generation DNA sequencing of acute myeloid leukemia (AML) patient samples has revealed novel recurrent mutations while at the same time highlighting the genetic heterogeneity of the disease. These observations suggest that an extraordinarily large number of combinations of mutations can contrib...
ORGANISM(S): Homo sapiens 
2017-05-02 | E-GEOD-70755 | biostudies-arrayexpress
TranscriptomicsIntegrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets [RNA-Seq_normal]
Next generation DNA sequencing of acute myeloid leukemia (AML) patient samples has revealed novel recurrent mutations while at the same time highlighting the genetic heterogeneity of the disease. These observations suggest that an extraordinarily large number of combinations of mutations can contrib...
ORGANISM(S): Homo sapiens 
2017-05-02 | E-GEOD-71689 | biostudies-arrayexpress
TranscriptomicsIntegrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (Leukemia Cell Bank)
Next generation DNA sequencing of acute myeloid leukemia (AML) patient samples has revealed novel recurrent mutations while at the same time highlighting the genetic heterogeneity of the disease. These observations suggest that an extraordinarily large number of combinations of mutations can contrib...
ORGANISM(S): Homo sapiens 
2017-05-02 | E-GEOD-72061 | biostudies-arrayexpress
TranscriptomicsIntegrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets [RNA-Seq_AML]
Next generation DNA sequencing of acute myeloid leukemia (AML) patient samples has revealed novel recurrent mutations while at the same time highlighting the genetic heterogeneity of the disease. These observations suggest that an extraordinarily large number of combinations of mutations can contrib...
ORGANISM(S): Homo sapiens 
2017-05-02 | E-GEOD-71686 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse FLA2 (highest LHSC frequency) and FLB1 (lowest LHSC frequency) leukemias
Expression profile of FLA2 (highest LSC frequency) and FLB1 (lowest LSC frequency) leukemias.
ORGANISM(S): Mus musculus 
2010-03-31 | E-MEXP-1597 | biostudies-arrayexpress
UnknownUnraveling the Potential of Small Molecule Heparin Glycomimetics in Neuroregenerative Therapeutics.
Not available
S-EPMC12715788 | biostudies-literature
UnknownRecurrent somatic BRAF insertion (p.V504_R506dup): a tumor marker and a potential therapeutic target in pilocytic astrocytoma.
Not available
S-EPMC6484687 | biostudies-literature
TranscriptomicsRNAi profiling by array of mouse hematopoietic stem cells infect ed with shPRox1 or shLuciferase
Global gene expression profiles of shProx1 vs. shLuciferase infected mouse hematopoietic stem cells.
ORGANISM(S): Mus musculus 
2010-08-01 | E-MTAB-290 | biostudies-arrayexpress
UnknownIDH1 as a Cooperating Mutation in AML Arising in the Context of Shwachman-Diamond Syndrome.
Not available
S-EPMC6702516 | biostudies-literature
UnknownRNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
Not available
S-EPMC5289888 | biostudies-literature
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