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TranscriptomicsmiRNA expression profiling of human monocyte-derived dendritic cells (moDCs) during maturation
miRNA expression profiling of human monocyte-derived dendritic cells (moDCs) during maturation. Immature, 4h and 16h LPS-activated moDCs were used. In this study were analysed 2 biological samples of RNA extracted from 4h-post LPS stimulation moDCs and 2 bfrom 16h-post LPS stimulation. The RNA ...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-13369 | biostudies-arrayexpress
TranscriptomicsFine-tuning of human dendritic cells regulation revealed by translational profiling
Dendritic cells (DCs) are the sentinels of the mammalian immune system and they undergo a complex maturation process mediated by activation upon pathogen detection. Recent studies described the analysis of activated DCs by transcriptional profiling, but translation regulation was never taken in acco...
ORGANISM(S): Homo sapiens 
2009-12-30 | E-GEOD-14000 | biostudies-arrayexpress
TranscriptomicsmiR-155 KO in human dendritic cells
In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation (maturation) that exhibits specific mechanisms to control immunity. Here, we show that in response to Lipopolysaccharides (LPS), several microRNAs (miRNAs) are regulated in human monocyte-deri...
ORGANISM(S): Homo sapiens 
2009-03-04 | E-GEOD-13296 | biostudies-arrayexpress
TranscriptomicsDendritic cells and stress translation
In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation that exhibits specific mechanisms to control the immune response. Here we show that in response to polyriboinosinic:polyribocytidylic acid (poly I:C), DCs mount a specific transcription progra...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-18115 | biostudies-arrayexpress
TranscriptomicsCopy number profiling via ArrayCGH on high grade serous epithelial ovarian cancer samples from multiple biopsies
We performed Array CGH on 25 patients with high grade serous epithelial ovarian cancer (HGS-EOC): each of this had multiple biopsies taken at the moment of the surgery in different anatomical sites, and 18 had also temporal biopsies taken after several cycles of chemotherapy. Blood was used as contr...
ORGANISM(S): Homo sapiens 
2019-12-19 | E-MTAB-6900 | biostudies-arrayexpress
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