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Friedreich’s ataxia (FRDA; OMIM 229300), an autosomal recessive neurodegenerative mitochondrial disease, is the most prevalent hereditary ataxia. In addition, FRDA patients showed additional non-neurological features such as scoliosis, diabetes and cardiac complications. Hypertrophic cardiomyopathy,...
ORGANISM(S): Homo sapiens 
This experiment investigates the relationship between maternal fluoride exposure during pregnancy and DNA methylation patterns in the placenta, aiming to identify epigenetic alterations associated with reduced kidney volume at birth. Placental samples were collected from term deliveries and classifi...
ORGANISM(S): Homo sapiens 

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights
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