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ProteomicsMucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human endo- and ecto-cervix chips
Modulation of mucus production by the human ecto- and endo-cervical epithelium by steroid hormones and associated interactions with commensal microbiome play a central role in the physiology and pathophysiology of the female reproductive tract. However, most of our knowledge about these interactions...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-26 | MSV000091806 | MassIVE
TranscriptomicsMacrophage gene expression associated with remodeling of the prepartum rat cervix: Microarray and pathway analyses
As the critical gatekeeper for birth, prepartum remodeling of the cervix is associated with increased resident macrophages (MM-OM-^F), proinflammatory processes, and extracellular matrix degradation. This study tested the hypothesis that expression of genes unique to MM-OM-^Fs characterizes the prep...
ORGANISM(S): Rattus norvegicus 
2015-01-27 | E-GEOD-65265 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of the bovine cervix at 6 timepoints during the peri-oestrus period.
The estrous cycles of Limousin heifers (n = 30) were synchronized by insertion of a controlled internal drug release (CIDR) device (1.94 g progesterone; Pfizer Animal Health) placed into the vagina for 8 days. A 0.5 mg intramuscular injection of a prostaglandin F2α (PG) analogue (PG, Estrumate, Sher...
ORGANISM(S): Bos taurus 
2013-01-04 | E-GEOD-38225 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human uterus before and after the onset of labor
We compared gene expression profiles in uterus before and after onset of labor. Gene expression profiles were compared between functionally distinct areas of the human uterus: the fundus, lower segment and the cervix in samples obtained before labor and during labor.
ORGANISM(S): Homo sapiens 
2005-04-01 | E-MEXP-106 | biostudies-arrayexpress
TranscriptomicsHuman_SAGE_cervix_normal_B_1
Uterine cervix normal SAGE, CGAP non-normalized SAGE library, bulk method , HPV negative This GEO Series was created by the GEO staff as part of a cleanup effort to ensure that all GEO Samples are included within a Series entry.
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-25753 | biostudies-arrayexpress
ProteomicsComparative analysis of CVF proteome composition during neoplastic transformation of cervix among females of reproductive age
The aim of this study is characterization of proteomic composition of the CVF for assessing the severity of HPV-associated intraepithelial neoplasias of the cervix among women of reproductive age.
ORGANISM(S): Homo sapiens (Human) 
2021-11-15 | PXD011472 | Pride
Lc-ms/ms Hpv Cervical cancer Cvf 
TranscriptomicsGene expression studies in normal, dysplastic and malignant cervical tissues
Gene expression profiling of normal cervix, CIN's and cancer cervix, with an intent to identify genes involved in the malignant transformation of normal cervix and to identify genes which can be used as biomarkers for early diagnosis. Identification of genes for predicting radiation response using m...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-14404 | biostudies-arrayexpress
TranscriptomicsDysregulation of miRNA in adenocarcinoma of the uterine cervix
We identified an altered miRNA expression in adenocarcinoma of the uterine cervix compared with normal cervix and futhermore analyzed their association with clinicopthologic characteristics. miRNA expression was measured in four cancerous tissues from the cervical adenocarcinoma and four non-cancero...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-55478 | biostudies-arrayexpress
GenomicsVaginal microbiota, cervix microbiota, uterine microbiota
Vaginal microbiota, cervix microbiota, uterine microbiota Raw sequence reads
PRJNA774109 | ENA
TranscriptomicsStability of miRNA in FFPE tumour samples exhibiting degraded mRNA [Cervix samples miRNA]
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits ability to expression profile, we explored factors predicting success for FFPE profiling and investigated an approach overcoming this limitation. Methods: Bladder (n=141, stored 3-8 years) and cervix (n=160, stored...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-39015 | biostudies-arrayexpress
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