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ProteomicsTargeting of CGRP signaling reverses maladaptive neurogenic immunosuppression in head and neck squamous cell carcinoma
Neurogenic inflammation is one component that sculpts the immune milieu of solid tumors. However, it remains unclear how the sensory-neuroimmune axis shapes the immune microenvironment in cold tumors to bolster treatment resistance. Using orthotopic head and neck squamous cell carcinoma (HNSCC) mode...
ORGANISM(S): Homo sapiens (Human) 
2026-09-10 | PXD081773 | Pride
Cgrp signaling Head and neck squamous cell carcinoma 
GenomicsNociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth
PRJNA1147658 | ENA
GenomicsMeningeal lymphatic CGRP signaling governs pain via cerebrospinal fluid efflux and neuroinflammation in migraine models
Meningeal lymphatic CGRP signaling governs pain via cerebrospinal fluid efflux and neuroinflammation in migraine models
PRJNA1107583 | ENA
GenomicsPAC1 constrains type II inflammation through promotion of CGRP signaling in ILC2s [RNA-seq]
PAC1 constrains type II inflammation through promotion of CGRP signaling in ILC2s [RNA-seq]
PRJNA1138422 | ENA
GenomicsPAC1 constrains type II inflammation through promotion of CGRP signaling in ILC2s [FastATAC-seq]
PAC1 constrains type II inflammation through promotion of CGRP signaling in ILC2s [FastATAC-seq]
PRJNA1138423 | ENA
GenomicsPAC1 constrains type II inflammation through promotion of CGRP signaling in ILC2s [scRNA-seq]
PAC1 constrains type II inflammation through promotion of CGRP signaling in ILC2s [scRNA-seq]
PRJNA1138424 | ENA
GenomicsSingle-cell sequencing uncovers sensory neuron–mediated CGRP signaling as a driver of sarcoma progression
Single-cell sequencing uncovers sensory neuron–mediated CGRP signaling as a driver of sarcoma progression
PRJNA1061471 | ENA
UnknownDirect interactions between calcitonin-like receptor (CLR) and CGRP-receptor component protein (RCP) regulate CGRP receptor signaling.
Not available
S-EPMC3320266 | biostudies-literature
GenomicsCGRP signaling Links Tumor-Associated Pain to Immune Evasion in Oral Squamous Cell Carcinoma
CGRP signaling Links Tumor-Associated Pain to Immune Evasion in Oral Squamous Cell Carcinoma
PRJNA1399335 | ENA
TranscriptomicsNociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth
Endometriosis is a debilitating and painful gynecological inflammatory disease affecting approximately 15% of women. Current treatments are ineffective for a significant fraction of patients, underscoring the need for new medical therapies with long-term benefits. Given the relevance of neuroimmune ...
ORGANISM(S): Mus musculus 
2025-08-09 | GSE274685 | GEO
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