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Type 1 diabetes patients received a daily subcutaneous injection of placebo or 0.33, 1 or 3 Millions IU of interleukin-2 (IL-2) for 5 consecutive days. Transcriptomic analysis was performed on PBMCs collected from patients before and after the IL-2 course.
ORGANISM(S): Homo sapiens 
Systemic lupus erythematosus (SLE) is a T and B cell-dependent autoimmune disease characterized by the appearance of autoantibodies, a global regulatory T cells (Tregs) depletion and an increase in Th17 cells. Recent studies have shown the multifaceted immunomodulatory effects of vitamin D, notably ...
ORGANISM(S): Homo sapiens 
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