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TranscriptomicsHigh-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes
Inflammatory breast cancer (IBC) is an aggressive form of BC poorly defined at the molecular level. We compared the molecular portraits of 63 IBC and 134 non-IBC (nIBC) clinical samples. Genomic imbalances of 49 IBCs and 124 nIBCs were determined using high-resolution array-comparative genomic hybri...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-23720 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of ERBB2-amplified breast cancers
15-25% of breast cancers (BC) show ERBB2-amplification and overexpression of the encoded ERBB2 tyrosine kinase receptor. They are associated with a poor prognosis but can benefit from targeted therapy. A better knowledge of these BCs may help understand their behavior and design new therapeutic stra...
ORGANISM(S): Homo sapiens 
2009-09-02 | E-GEOD-17907 | biostudies-arrayexpress
UnknownFibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13).
Not available
S-EPMC20444 | biostudies-literature
TranscriptomicsGenome profiling of pancreatic adenocarcinoma
Pancreatic adenocarcinoma is one of the most aggressive human cancers and displays many different chromosomal abnormalities and mutations. By using 244K high-resolution array-comparative genomic hybridization (aCGH) we studied the genome alterations of 39 fine-needle aspirations from pancreatic aden...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-MTAB-570 | biostudies-arrayexpress
UnknownA benchmarking study of individual somatic variant callers and voting-based ensembles for whole-exome sequencing.
Not available
S-EPMC11790059 | biostudies-literature
UnknownDown-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer.
Not available
S-EPMC3218004 | biostudies-literature
UnknownStromal Expression of MARCKS Protein in Ovarian Carcinomas Has Unfavorable Prognostic Value.
Not available
S-EPMC5795991 | biostudies-literature
UnknownPrognostic and predictive value of PDL1 expression in breast cancer.
Not available
S-EPMC4467160 | biostudies-literature
Transcriptomicsbreast cancer cell lines ALDH+/-
Self-renewal and differentiation are two epigenetic programs that regulate pluripotency of stem cells. During oncogenesis, dysregulation of these two programs leads to the development of cancer stem cells (CSCs). Here, we used a pan genomic promoter microarray to determine the DNA methylation portra...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-MTAB-2236 | biostudies-arrayexpress
TranscriptomicsInvestigation of molecular features involved in clinical responses and survival in advanced endometrial carcinoma
Hormone therapy (HT) is an effective treatment for metastatic endometrial carcinoma (mEC), with limited toxicity and low cost. We focused on molecular analysis of mECs treated by HT and, for the first time to date, we compared genomic profiles of paired metastasis and primary ECs. The main objective...
ORGANISM(S): Homo sapiens 
2022-03-16 | E-MTAB-11552 | biostudies-arrayexpress
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