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UnknownChAHP2 and ChAHP control diverse retrotransposons by complementary activities.
Not available
S-EPMC11293393 | biostudies-literature
GenomicsThe ChAHP complex counteracts chromatin looping at Ctcf sites that have emerged from recent SINE expansions
The ChAHP complex counteracts chromatin looping at Ctcf sites that have emerged from recent SINE expansions
PRJNA515300 | ENA
GenomicsThe ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers
The ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers
PRJNA1092595 | ENA
GenomicsThe ChAHP complex counteracts chromatin looping at Ctcf sites that have emerged from recent SINE expansions
Ctcf and cohesin are key players in the three dimensional organization of chromatin. Whereas genome-wide Ctcf binding has diverged substantially between species due to transposon-mediated motif expansions, demarcation of topologically associating domains (TADs) by Ctcf is remarkably well conserved. ...
ORGANISM(S): Mus musculus 
2019-09-05 | GSE125129 | GEO
GenomicsChAHP Displaces Transcriptional Regulators Through Active Chromatin Remodeling [RNAseq]
ChAHP Displaces Transcriptional Regulators Through Active Chromatin Remodeling [RNAseq]
PRJNA1266618 | ENA
GenomicsChAHP Displaces Transcriptional Regulators Through Active Chromatin Remodeling [gNOMEseq]
ChAHP Displaces Transcriptional Regulators Through Active Chromatin Remodeling [gNOMEseq]
PRJNA1266605 | ENA
GenomicsChAHP Displaces Transcriptional Regulators Through Active Chromatin Remodeling [ChIPseq]
ChAHP Displaces Transcriptional Regulators Through Active Chromatin Remodeling [ChIPseq]
PRJNA1266620 | ENA
TranscriptomicsThe ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers
Although chromatin remodellers are among the most important risk genes associated with neurodevelopmental disorders (NDDs), the roles of these complexes during brain development are in many cases unclear. Here, we focused on the recently discovered ChAHP chromatin remodelling complex. The zinc finge...
ORGANISM(S): Mus musculus 
2024-12-30 | GSE262584 | GEO
GenomicsChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment [RNA-seq]
ChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment [RNA-seq]
PRJNA1266249 | ENA
GenomicsChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment [ChIP-seq]
ChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment [ChIP-seq]
PRJNA1266252 | ENA
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