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To compare the gene expression profiles of leukemia initiation cells of SALL4B transgenic mice and their control counterparts.
ORGANISM(S): Mus musculus 
The overall survival of lung cancer patients remains dismal despite the availability of targeted therapies. Oncofetal protein SALL4 is a novel cancer target. We herein report that SALL4 was aberrantly expressed in a subset of lung cancer patients with poor survival. SALL4 silencing by RNA interferen...
ORGANISM(S): Homo sapiens 
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Treatment of HCC remains abysmal; discovery of novel pathways implicated in hepatocarcinogenesis is needed for more effective therapeutics. SALL4 is a stem cell factor essential for the maintenance of embry...
ORGANISM(S): Homo sapiens 
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