Chai Z Z - OmicsDI

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Unknown (1928)
Proteomics (41)
Transcriptomics (9)
Metabolomics (8)

Organisms

Homo sapiens (26)
Mus musculus (11)
Arabidopsis thaliana (4)
Populus hybrid cultivar (1)
Saccharomyces cerevisiae (1)
Staphylococcus aureus (1)
Staphylococcus aureus subsp. aureus NCTC 8325 (1)
Alligator sinensis (1)
Dunaliella salina (1)
Physalis angulata (1)
Sus scrofa domesticus (1)
Trichoplusia ni (1)

Repository

pride (28)
iProX (12)
biostudies-arrayexpress (9)
MetaboLights (8)
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Cell culture (5)
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Pancreatic islet beta cell (1)
Pancreatic islet cell (1)
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Disease

Adult hepatocellular carcinoma (1)
Disease free (1)
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Liver cancer (1)
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Pancreatic ductal adenocarcinoma (1)
Severe acute respiratory syndrome (1)
Type 2 diabetes mellitus (1)

Technology Type

Mass Spectrometry (28)
Shotgun proteomics (11)
Mass spectrometry (8)
Bottom-up proteomics (7)
Data-dependent acquisition (7)
Affinity purification coupled with mass spectrometry proteomics (2)
Gel-based experiment (2)
DiaPASEF (1)
Mass spectrometry imaging (1)
SRM/MRM (1)
SWATH MS (1)

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Liquid Chromatography MS - negative - reverse phase (6)
Liquid Chromatography MS - positive - reverse phase (6)
LTQ Orbitrap (1)
Agilent 7890 (1)
Liquid Chromatography MS - (1)

Publication Date

2025 (14)
2021 (7)
2024 (6)
2022 (5)
2026 (4)
2023 (4)
2020 (4)
2018 (3)
2015 (2)
2012 (2)
2008 (2)
2019 (2)
2013 (1)
2011 (1)
2007 (1)

CHEBI ID

CHEBI:15843 (3)
CHEBI:15887 (3)
CHEBI:15891 (3)
CHEBI:16015 (3)
CHEBI:16027 (3)
CHEBI:16040 (3)
CHEBI:16196 (3)
CHEBI:16217 (3)
CHEBI:16335 (3)
CHEBI:16704 (3)
CHEBI:16919 (3)
CHEBI:17154 (3)
CHEBI:17351 (3)
CHEBI:17368 (3)
CHEBI:17509 (3)
CHEBI:17568 (3)
CHEBI:17596 (3)
CHEBI:28875 (3)
CHEBI:30769 (3)
CHEBI:30805 (3)
CHEBI:36751 (3)
CHEBI:7916 (3)
CHEBI:10319 (2)
CHEBI:104011 (2)
CHEBI:1148 (2)
CHEBI:15344 (2)
CHEBI:15354 (2)
CHEBI:15355 (2)
CHEBI:15428 (2)
CHEBI:15551 (2)

Metabolite Name

Adenosine (3)
Creatinine (3)
Cytosine (3)
Hypoxanthine (3)
Kynurenic acid (3)
5'-methylthioadenosine (2)
Betaine (2)
Biotin (2)
Choline (2)
Citramalic acid (2)
Coumarin (2)
Creatine (2)
Cytidine (2)
D-Mannose (2)
Hispidulin (2)
L-Glutamine (2)
L-Valine (2)
L-glutamic acid (2)
Linoleic acid (2)
N-Acetylneuraminic acid (2)
Nicotinamide (2)
Palmitic acid (2)
Phenyl acetate (2)
Phenylacetic acid (2)
Phenylacetylglycine (2)
Salicylic acid (2)
Taurine (2)
Theophylline (2)
Uracil (2)
Uric acid (2)

Study type

Transcription profiling by array (4)
RNA-seq of coding RNA (3)
ChIP-chip by tiling array (1)
Transcription profiling by tiling array (1)

Release Date

2025 (313)
2022 (307)
2024 (251)
2023 (247)
2021 (198)
2020 (144)
2019 (105)
2018 (74)
2017 (60)
2016 (52)
2015 (45)
2026 (42)
2014 (31)
2012 (22)
2013 (18)
2011 (10)
2008 (7)
2010 (5)
2009 (5)
2007 (1)

Lab affiliation

Westlake University (2)
1 Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2 Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3 Taikang Center for Life and Medical Sciences of Wuhan University (1)
1Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3Taikang Center for Life and Medical Sciences of Wuhan University (1)
1Department of Pathology, Dana-Farber/Harvard Cancer Center, PhD Program in Immunology, Harvard Medical School; Department of Laboratory Medicine, Boston Children's Hospital, Enders Research Building, Room 811, Boston, MA, 02115, USA (1)
1State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, School of Medicine, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 210096, China.2 Co-Innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China. (1)
Basic Immune System of Plants / Protein Mass SpectrometryMax Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (1)
Biomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia (1)
College of Life Science, Northwest University (1)
College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China. (1)
Dalian Ocean University, China. 116023 (1)
Department of Biochemistry Biophysics and Structural Biology, Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis, St. Louis, Missouri, United States (1)
Department of Biochemistry, Department of Oncology, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada (1)
Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China (1)
Department of Molecular Genetics, Erasmus University Medical Center, Erasmus MC Cancer Institute; Dr. Molewaterplein 40, 3015GD Rotterdam, The Netherlands (1)
Department of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (1)
Department of Radiation Oncology, UNC-Chapel Hill (1)
Departments of Cancer Genetics and Epigenetics Beckman Research Institute, City of Hope, Duarte, CA 91007, USA (1)
Division of Metabolism, Endocriology & Diabetes and Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48105, USA. (1)
Doctor at Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China (1)
Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education and State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University (1)
MOE Key Laboratory of Biosystems Homeostasis & Protection, State Conservation Centre for Gene Resources of Endangered Wildlife, College of Life Sciences, Zhejiang University, Hangzhou 310058, P. R. China (1)
NHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, China; (1)
Proteomics center, Erasmus MC (1)
School of Animal Science and Technology, Genetic Breeding and Reproduction Laboratory, Southwest University, China;Chongqing Academy of Animal Husbandry Sciences, Pig Breeding Research Institute, China (1)
The Francis Crick Institute 1 Midland Road London, NW1 1AT UK (1)
The University of Melbourne (1)
xuzhu medical university (1)

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Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea via TGR5-FAK-RhoA/Rock signaling revealed by integrated metabolomics and proteomics

Irinotecan (CPT-11) is widely used for colorectal cancer treatment, with delayed-onset diarrhea as its primary side effect. Xiao-Chai-Hu-Tang (XCHT) has been clinically observed to alleviate diarrhea, but its mechanisms remain unclear. This study aimed to explore the underlying regulatory mechani...

2025-09-03 | MTBLS12931 | MetaboLights

SRSF3 and hnRNP A1-mediated m6A-modified circCDK14 regulates intramuscular fat deposition by acting as miR-4492-z sponge.

Not available

S-EPMC11881307 | biostudies-literature

(Z)-3-(3,4-Dimeth-oxy-phen-yl)-3-(4-fluoro-phen-yl)-1-morpholino-prop-2-en-1-one.

Not available

S-EPMC3151755 | biostudies-literature

Xiao-Chai-Hu-Tang Ameliorates Depressive Symptoms via Modulating Neuro-Endocrine Network in Chronic Unpredictable Mild Stress-Induced Mice.

Not available

S-EPMC11843474 | biostudies-literature

Targeted bile acid profiles reveal the liver injury amelioration of Da-Chai-Hu decoction against ANIT- and BDL-induced cholestasis.

Not available

S-EPMC9437253 | biostudies-literature

Network pharmacology and molecular docking study on the mechanism of colorectal cancer treatment using Xiao-Chai-Hu-Tang.

Not available

S-EPMC8202922 | biostudies-literature

Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.

Not available

S-EPMC9296287 | biostudies-literature

Da-Chai-Hu Decoction Ameliorates High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Through Remodeling the Gut Microbiota and Modulating the Serum Metabolism.

Not available

S-EPMC7732620 | biostudies-literature

Transcription profiling of human prostate cancer cells with arachidonic acid reveals induction of 11 genes that are regulated by NFkappaB

Essential fatty acids (FA) are not only energy-rich molecules; they are also an important component of the membrane bilayer and recently have been implicated in induction of fatty acid synthase (FAS) and other genes. Using gene chip analysis, we have found that arachidonic acid (AA), an omega-6 fat...

ORGANISM(S): Homo sapiens

2007-07-03 | E-GEOD-3737 | biostudies-arrayexpress

Real-World Study on Chai-Shi-Jie-Du Granules for the Treatment of Dengue Fever and the Possible Mechanisms Based on Network Pharmacology.

Not available

S-EPMC10482559 | biostudies-literature

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