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TranscriptomicsNovel anti-inflammatory activity of chlorojanerin isolated from Sausurrea heteromalla (D. Don) Hand.-Mazz.
Medicinal plants have shown great promise as a source of novel drug compounds for the treatment of inflammatory disorders. In our search for new entities with anti-inflammatory potential, the extracts of the whole plant of Saussurea heteromalla (family-Asteraceae), collected from Himalayas, were ev...
ORGANISM(S): Homo sapiens 
2011-12-14 | E-GEOD-34180 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of decidualized human endometrial stromal cells knockdown for HOXA10
The homeobox gene HOXA10 plays a key role in endometrial differentiation during embryogenesis and is abundantly expressed in the adult endometrium and decidual cells. In the adult endometrium the expression of HOXA10 is regulated by estrogen and progesterone and the levels are highest in the decidua...
ORGANISM(S): Homo sapiens 
2012-02-14 | E-GEOD-35801 | biostudies-arrayexpress
TranscriptomicsModulation of host gene expression by Hepatitis E virus ORF3 protein
Analysis of human liver cell line (Huh7) infected with HEV ORF3 expressing (Ad-orf3-egfp) and control recombinant adenovirus (Ad-egfp). Hepatitis E virus ORF3 protein (pORF3) is known to modulate the host cell. Results provide insight into the role of this protein for HEV infection and pathogenesis....
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-23412 | biostudies-arrayexpress
TranscriptomicsCDK-4 inhibitor P276-00 sensitizes Pancreatic Cancer cells to Gemcitabine induced Apoptosis
Despite advances in molecular pathogenesis, pancreatic cancer remains a major unsolved health problem. It is a rapidly invasive, metastatic tumor that is resistant to standard therapies. The phosphatidylinositol-3-kinase (PI3K)/Akt and mammalian target of rapamycin (mTOR) signaling pathways are freq...
ORGANISM(S): Homo sapiens 
2012-03-23 | E-GEOD-36703 | biostudies-arrayexpress
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