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UnknownConsequences of EMT-Driven Changes in the Immune Microenvironment of Breast Cancer and Therapeutic Response of Cancer Cells.
Not available
S-EPMC6572359 | biostudies-literature
TranscriptomicsLM2 cell: infected with lentivirus to stably express Elf5 vs GFP
Elf5 induced transcriptional changes in high lung metastasis subline LM2 (MDA-MB-231 origin), control (GFP) vs ELF5 Two-condition experiment, control (GFP) vs Elf5. Each has duplicate biological repeats.
ORGANISM(S): Homo sapiens 
2012-09-20 | E-GEOD-32143 | biostudies-arrayexpress
UnknownDll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway.
Not available
S-EPMC7813834 | biostudies-literature
UnknownLoss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling.
Not available
S-EPMC8237104 | biostudies-literature
UnknownNotch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche.
Not available
S-EPMC7881440 | biostudies-literature
UnknownEstrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer.
Not available
S-EPMC6756232 | biostudies-literature
OtherSirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.
Data from ProteomeXchange, PXD ID: PXD001447. Experiment: SIRT4_MITO_MOCK1, file: SIRT4_MITO_MOCK1_05.mzml. Published as part of Cell. 2014 Dec 18;159(7):1615-25 . From the Abstract: {{i}} ... Here, we establish SIRT4 as a cellular lipoamidase that regulates the pyruvate dehydrogenase complex (PDH)...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320006423 | GPMDB
Resource Reanalysis 
TranscriptomicsExpression data from mice mammary glands from Elf5 knockout (KO) and wildtype controls
We developed conditional knockout mice where the transcription factor Elf5 (also called ESE-2) is deleted in the mammary glands. Loss of Elf5 results in block in alveologenesis and epithelial differentiation defects. Mammary gland samples from Elf5 knockout and wild type animals were analyzed for gl...
ORGANISM(S): Mus musculus 
2012-09-01 | E-GEOD-32103 | biostudies-arrayexpress
ProteomicsAP-MS analysis of sirtuin-4 interactions in human fibroblasts
Sirtuins (SIRTs) form a critical family of nicotinamide adenine dinucleotide (NAD)-dependent enzymes that govern genome regulation, metabolism, and aging. Despite conserved deacetylase domains, SIRTs4-7 have little to no deacetylase activity, and a robust catalytic activity for mitochondrial SIRT4 h...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-04 | MSV000079557 | MassIVE
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