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MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
Unknown[225Ac]Ac- and [111In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts.
Not available
S-EPMC10522541 | biostudies-literature
UnknownPreclinical Comparison of [<sup>111</sup>In]In- and [<sup>225</sup>Ac]Ac-DOTA-Trastuzumab IgG, F(ab')<sub>2</sub> and Fab for Theranostic SPECT/CT Imaging and α-Particle Radioimmunotherapy of HER2-Positive Human Breast Cancer.
Not available
S-EPMC11708818 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownCorticothalamic synchronization leads to c-fos expression in the auditory thalamus.
Not available
S-EPMC1913871 | biostudies-literature
UnknownReduced cognitive function during a heat wave among residents of non-air-conditioned buildings: An observational study of young adults in the summer of 2016.
Not available
S-EPMC6039003 | biostudies-literature
UnknownInteractions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies.
Not available
S-EPMC10329203 | biostudies-literature
UnknownBuilding Vulnerability in a Changing Climate: Indoor Temperature Exposures and Health Outcomes in Older Adults Living in Public Housing during an Extreme Heat Event in Cambridge, MA.
Not available
S-EPMC6651653 | biostudies-literature
UnknownUsability and Perceived Usefulness of the AFib 2gether Mobile App in a Clinical Setting: Single-Arm Intervention Study.
Not available
S-EPMC8663604 | biostudies-literature
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