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TranscriptomicsMock or latently infected KSHV cells (BCBL, SLK and HFF)
[original title] Mock or latently infected KSHV cells (BCBL, SLK and HFF) vs common reference (mixture of RNA from both infected and uninfected cells). Expression profiling of latently infected cells using a custom tiling microarray. SLK and HFF cells were infected and selected for rKSHV.219. Mock ...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-20443 | biostudies-arrayexpress
TranscriptomicsMock or KSHV cells (BJABJ, BCBL, TIME and HUVEC) vs common reference (mixture of RNA from both infected and uninfected cells)
Expression profiling of latently infected cells using a custom tiling microarray HUVEC and TIME cells were infected BCBL-1-derived KSHV. Mock infected HUVEC and TIME cells served as controls for each of these two stably infected cells, respectively. BJAB cells served as uninfected controls for the B...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-21972 | biostudies-arrayexpress
TranscriptomicsA Core MYC Gene Expression Signature is prominent in basal-like cancer
BACKGROUND: The MYC oncogene contributes to induction and growth of many cancers but the full spectrum of the MYC transcriptional response remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: Using microarrays, we conducted a detailed kinetic study of genes that respond to MYCN or MYCNDeltaMBII inducti...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-15523 | biostudies-arrayexpress
Transcriptomics40 IPF patients and 8 healthy controls
There is microscopic spatial and temporal heterogeneity of pathologic changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiological mediators of disease and clinical progression. We measured gene expression in samples from lung biopsies or explan...
ORGANISM(S): Homo sapiens 
2014-10-14 | E-GEOD-53845 | biostudies-arrayexpress
TranscriptomicsMyeloid cells or lung fibroblasts treated with IL-4 or IL-13
IL-4 and IL-13 are cytokines involved in type 2 immune responses involved in atopic asthma and other diseases. They have a partially overlapping set of cognate receptors whose roles are incompletely understood. Here we explore the effects of these cytokines on various cells related to human lung dis...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-47538 | biostudies-arrayexpress
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