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TranscriptomicsExpression data of ALDH+ breast cancer cells
It has been suggested that breast cancers are driven and maintained by a cellular subpopulation with stem cell properties. These breast cancer stem cells (BCSCs) mediate metastasis and by virtue of their resistance to radiation and chemotherapy, contribute to relapse. Although several BCSC markers ...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-GEOD-52327 | biostudies-arrayexpress
TranscriptomicsCandidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling
To better understand Luminal B subtype we studied in 188 breast cancers of various molecular subtypes, DNA copy number aberrations (CNAs), DNA promoter methylation and gene expression profiles. Please note mRNA expression data already submitted for study: E-GEOD-21653.
ORGANISM(S): Homo sapiens 
2014-01-01 | E-MTAB-1861 | biostudies-arrayexpress
TranscriptomicsA stemness-related ZEB1-MSRB3 axis governs cellular pliancy and cancer genome stability.
Genomic instability is a prominent driver of tumorigenesis. However, a significant fraction of human cancers display few genomic aberrations, suggesting alternative roads towards malignancy. Here, we show that the differentiation status of normal human mammary epithelial cells influences the early r...
ORGANISM(S): Homo sapiens 
2017-03-23 | E-MTAB-4145 | biostudies-arrayexpress
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