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MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
ProteomicsGlobal acetylomics of Campylobacter jejuni shows lysine acetylation regulates CadF adhesin processing and fibronectin binding during in vivo-like growth
Campylobacter jejuni is the leading cause of acute bacterial gastroenteritis in the developed world. Despite the prevalence of infection, the pathogenesis of C. jejuni remains poorly understood. Lysine acetylation (KAc) is a reversible post-translational modification (PTM) that can alter the protein...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 
2025-03-11 | PXD042815 | Pride
Metabolism Lysine acetylation Post-translational modifications Bacterial virulence Membrane proteins 
UnknownMeta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.
Not available
S-EPMC5299468 | biostudies-literature
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