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TranscriptomicsGene expression changes induced by BRD9876 in MM1S cells
The goal of this study was to identify transcriptional changes induced by a novel compound BRD9876 as a starting point to identify the compound's mechanism of action. Compound-treated cells are compared in duplicate with cells treated vehicle control (DMSO).
ORGANISM(S): Homo sapiens 
2014-12-16 | E-GEOD-64178 | biostudies-arrayexpress
TranscriptomicsNiche-based screening identifies small-molecule inhibitors of leukemia stem cells
Efforts to develop more effective therapies for acute leukemia may benefit from high-throughput screening systems that reflect the complex physiology of the disease, including leukemia stem cells (LSCs) and supportive interactions with the bone-marrow microenvironment. The therapeutic targeting of L...
ORGANISM(S): Mus musculus 
2013-09-20 | E-GEOD-51033 | biostudies-arrayexpress
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