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UnknownChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function.
Not available
S-EPMC3024787 | biostudies-literature
Genomics
Targeting CHCHD3-cGAS to Remodel Immunosuppressive Microenvironment in Lung Adenocarcinoma: Mechanism and Clinical Translation
PRJNA1304355 | ENA
TranscriptomicsCRISPR RNA-seq from HepG2 (ENCSR206ICZ)
RNA-seq on HepG2 cells treated with a CRISPR gRNA against CHCHD3. (CHCHD3-BGHcLV29) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2022-12-04 | GSE219577 | GEO
TranscriptomicsCRISPR RNA-seq from K562 (ENCSR307GHU)
RNA-seq on K562 cells treated with a CRISPR gRNA against CHCHD3. (CHCHD3-BGKcLV28) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2022-12-04 | GSE219663 | GEO
GenomicsTF ChIP-seq from K562 (ENCSR775NLJ)
eGFP-CHCHD3 ChIP-seq on human K562 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2022-07-22 | GSE209095 | GEO
UnknownMitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity.
Not available
S-EPMC10361721 | biostudies-literature
UnknownMic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Not available
S-EPMC5072434 | biostudies-literature
TranscriptomicsMetabolic adaptation of white adipose tissue to acute, short-term environmental oxygen restriction in mice
White adipose tissue (WAT) expansion during e.g. obesity reduces oxygen availability in WAT in mice. Little is known on the adaptation of WAT to mild environmental oxygen restriction (OxR). Therefore, we studied metabolic adaptation to acute OxR in fasted, diet-induced moderately obese mice that wer...
ORGANISM(S): Mus musculus 
2020-09-21 | GSE64238 | GEO
UnknownLoss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Not available
S-EPMC10797693 | biostudies-literature
UnknownPD-1 signaling affects cristae morphology and leads to mitochondrial dysfunction in human CD8+ T lymphocytes.
Not available
S-EPMC6567413 | biostudies-literature
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