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TranscriptomicsTranscriptional profiling of MLL5 Knock down vs. control C2C12 myoblasts (S phase enriched)
Knockdown of MLL5 led to deregulation of S phase. To understand the molecular basis for this phenotype, we performed microarray analysis of S phase synchronized myoblasts. Genes differentially regulated by MLL5 knock down were revealed by microarray analysis using NIA15K mouse chips. Control and kno...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-14931 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of PRDM2 Knockdown in proliferating, quiescent and differentiating myoblasts
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58676 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PRDM2 Knock down vs.controlGFPsh proliferating C2C12 Myoblasts
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of growing myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using NIA15K mouse chips. Control and knock down...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58675 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PRDM2 Knock down vs.controlGFPsh Quiescent C2C12 Myoblasts (G0 enriched)
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of quiescent myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using affymetrix mouse chips. Control and knoc...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58674 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PRDM2 Knock down vs.controlGFPsh differentiated C2C12 Myoblasts (D28hrs)
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of 28hr differentiated myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using affymetrix mouse chips. Contro...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58673 | biostudies-arrayexpress
TranscriptomicsDistinct transcriptional networks in quiescent myoblasts: a role for Wnt signaling in reversible vs irreversible arrest
Using cDNA arrays, we compared G0 myoblasts (S48) with post-mitotic myotubes. Our findings define the transcriptional program of quiescent myoblasts in culture which show important similarities with muscle satellite cells, and establish that distinct gene expression profiles characterize irreversibl...
ORGANISM(S): Mus musculus 
2013-04-16 | E-GEOD-33676 | biostudies-arrayexpress
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