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Chemoproteomic capture of RNA binding activity in living cells
Proteomic methods for RNA interactome capture (RIC) rely principally on crosslinking native or labeled cellular RNA to enrich and investigate RNA-binding protein (RBP) composition and function in cells. The ability to measure RBP activity at individual binding sites by RIC, however, has been more ch...
ORGANISM(S): Homo sapiens 
2023-10-12 | GSE240318 | GEO
Quantitative chemoproteomic profiling of protein crosslinks induced by methylglyoxal
ORGANISM(S): Homo Sapiens Mus Musculus 
2022-01-03 | PXD030688 |
Phenotypic screening is a valuable tool to both understand and engineer complex biological systems. We demonstrate the functionality of this approach in the development of cell-free protein synthesis (CFPS) technology. Phenotypic screening identified numerous compounds that enhanced protein produc...
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast) 
Protein lipoylation is an evolutionarily conserved post-translational modification (PTM) from prokaryotes and eukary-otes. Lipoylation is known to contribute to several human diseases including metabolic disorders, cancer and Alz-heimer’s disease. While individual lipoylated proteins have been bioch...
ORGANISM(S): Homo Sapiens Escherichia Coli 
2022-02-05 | PXD031466 |
Chemoproteomic Mapping of Glycolytic Targetome in Cancer Cells
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