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UnknownAMPKα1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation.
Not available
S-EPMC6962094 | biostudies-literature
ProteomicsDual human iPSC-derived cardiac lineage cell-seeding extracellular matrix patches promote regeneration and long-term repair of infarcted hearts
The LC-MS/MS-based in-depth proteomic analysis of the secretory proteins was performed using the CdM collected from the equal number of hCVPCs, hCMs and their 1:1 mixture. Then the label-free quantification of MS data and statistical analyses were used to compare the three groups.
ORGANISM(S): Homo Sapiens 
2025-02-24 | PXD061158 |
TranscriptomicsSIRT1 negatively regulates the differentiation of IL-9-producing CD4+T cells
Distinct metabolic programs support the differentiation of CD4+T cells into their separate lineages. In this study, we investigated metabolic mechanisms underlying the differentiation of IL-9 producing-CD4+T cells (TH9) in allergic airway inflammation and cancerous tumors. We found here that SIRT1 n...
ORGANISM(S): Mus musculus 
2016-06-14 | E-GEOD-79607 | biostudies-arrayexpress
ProteomicsThe mechanism of ATP6V0A1 regulating immune evasion in colorectal cancer
Our previous study showed the immunosuppressive ability of colorectal cancer cell-intrinsic ATP6V0A1. This project aimed to understand the mechanism of ATP6V0A1 regulating immune evasion in colorectal cancer (CRC). For this purpose, we used MS analysis to detect the changes in the protein expression...
ORGANISM(S): Mus Musculus 
2024-06-11 | PXD044010 |
ProteomicsDeep Multilayer Tissue Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression, human data
The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-17 | MSV000096123 | MassIVE
UnknownDigital ray: enhancing cataractous fundus images using style transfer generative adversarial networks to improve retinopathy detection.
Not available
S-EPMC11503040 | biostudies-literature
UnknownThe genetic determinants of recurrent somatic mutations in 43,693 blood genomes.
Not available
S-EPMC10132750 | biostudies-literature
UnknownDeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning.
Not available
S-EPMC12443585 | biostudies-literature
UnknownImmediate- or Delayed-Intensive Statin in Acute Cerebral Ischemia: The INSPIRES Randomized Clinical Trial.
Not available
S-EPMC11134282 | biostudies-literature
UnknownAberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
Not available
S-EPMC10360040 | biostudies-literature
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