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TranscriptomicsTranscription profiling of mouse muscle mutant to reveals skeletal muscle growth and fiber composition in mice are regulated through the transcription factors STAT5a/b
In skeletal muscle, STAT5a/b transcription factors are critical for normal postnatal growth, whole-animal glucose homeostasis, and local IGF-1 production. These observations have led us to hypothesize that STAT5a/b are critical for maintenance of normal muscle mass and function. To investigate thi...
ORGANISM(S): Mus musculus 
2009-09-05 | E-GEOD-14710 | biostudies-arrayexpress
UnknownGenomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.
Not available
S-EPMC4334774 | biostudies-literature
TranscriptomicsIntegration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia
B-cell precursor acute lymphoblastic leukemia (pre-B ALL) is the most common pediatric cancer. Although the genetic origin of the disease remains unclear, epigenetic modifications including DNA methylation are suggested to contribute significantly to leukemogenesis. We assessed the DNA methylation s...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-38235 | biostudies-arrayexpress
ProteomicsAcetylome profiling of bermudagrass stolons
Bermudagrass (Cynodon dactylon L.) is an important warm-season turfgrass species with well-developed stolons, which lay the foundation for fast propagation of bermudagrass plants through asexually clonal growth. However, the growth and development of bermudagrass stolons are still poorly understood ...
ORGANISM(S): Cynodon dactylon 
2022-08-20 | PXD034841 | Pride
Bermudagrass  cynodon dactylon  stolon  metabolism  acetylation 
ProteomicsSuccinlylome profiling of bermudagrass stolons
Bermudagrass (Cynodon dactylon L.) is an important warm-season turfgrass species with well-developed stolons, which lay the foundation for fast propagation of bermudagrass plants through asexually clonal growth. However, the growth and development of bermudagrass stolons are still poorly understood ...
ORGANISM(S): Cynodon dactylon 
2022-08-20 | PXD034808 | Pride
Bermudagrass  cynodon dactylon  stolon  metabolism  succinylation 
ProteomicsProteomic profiling of IBD circulating exosomes
Differential proteome profiling of IBD serum exosomes to find corresponding regulatory protein cargoes of serum exosomes in IBD progress. Exosomal proteins were extracted using SDT buffer lysis (4% SDS, 100mM Tris HCl, 1mM DTT, pH7.6), and the protein concentration was determined using the BCA prote...
ORGANISM(S): Homo Sapiens 
PXD043594 |
ProteomicsDiscovery of Novel MLKL PROTAC Degrader for the Treatment of Hepatocellular Carcinoma via Promoting Parthanatos
Chen et al. discovered a highly potent and selective MLKL-targeted PROTAC C116 that effectively induces MLKL degradation and promotes parthanatos in HCC cells. More significantly, C116 was able to induce in vivo MLKL degradation and exerts anti-tumor activities in an orthotopic HCC tumor model, posi...
ORGANISM(S): Mus Musculus 
PXD069462 |
UnknownDiscovery of a potent, covalent BTK inhibitor for B-cell lymphoma.
Not available
S-EPMC4027949 | biostudies-literature
ProteomicsBermudagrass stolon phosphoproteomics
As a widely used turfgrass species, bermudagrass (Cynodon dactylon L.) can be easily propagated by colonial growth of stolons. Previous studies collectively revealed that exotic environmental factors and intrinsic hormones and genes are all involved in the differentiation, development, and diageotro...
ORGANISM(S): Cynodon dactylon 
2019-09-25 | PXD014113 | Pride
Bermudagrass  cynodon dactylon  stolon  phosphoproteome 
ProteomicsComparative proteomics analyses of rhizomes and stolons in bermudagrass
As an important perennial warm-season turfgrass species, bermudagrass (Cynodon dactylon L.) form underground-growing rhizomes and aboveground-growing stolons simultaneously, making it a fast propagating clonal plant with strong regeneration ability. However, the intrinsic difference between the two ...
ORGANISM(S): Cynodon dactylon 
2021-05-06 | PXD021875 | Pride
Cynodon dactylon Proteome Bermudagrass Stolon Rhizome 
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