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TranscriptomicsEffects of hypothermia on gene expression in zebrafish gills
Ectothermic vertebrates are different from mammals that are sensitive to hypothermia and they have to maintain core temperature for survival. Why and how ectothermic animals can survive, grow and reproduce in low temperature have been for a long time a scientifically challenging and important inquir...
ORGANISM(S): Danio rerio 
2010-06-20 | E-GEOD-7853 | biostudies-arrayexpress
TranscriptomicsComparative profiling of primary colorectal carcinomas and liver metastases
PURPOSE: We sought to identify genes of clinical significance to predict survival and the risk for colorectal liver metastasis (CLM), the most common site of metastasis from colorectal cancer (CRC). PATIENTS AND METHODS: We profiled gene expression in 31 specimens from primary CRC and 32 unmatched s...
ORGANISM(S): Homo sapiens 
2011-03-22 | E-GEOD-22834 | biostudies-arrayexpress
TranscriptomicsGene expression in epithelial and non-epithelial cells of renal origin
We aimed to define epithelial-specific genes in the kidney. In the developing mouse kidney at E12.5 epithelial cells are restricted to the ureteric bud, while mesenchymal cells surrounding the ureteric bud are non-epithelial. The mouse renal epithelial cell line mIMCD-3 was used to represent kidney ...
ORGANISM(S): Mus musculus 
2010-09-23 | E-GEOD-24295 | biostudies-arrayexpress
TranscriptomicsTranscriptomic changes in response to mercury toxicity in rice roots
To gain more insight into cellular responses to mercury, we have undertaken a large-scale analysis of the rice transcriptome during mercury stress.More transcripts were responsive to mercury during short (pooled from 1- and 3-h treatments) , as compared to long (24 h) exposures. After short exposure...
ORGANISM(S): Oryza sativa 
2014-05-28 | E-GEOD-41719 | biostudies-arrayexpress
TranscriptomicsExpression data from one year old leaves of Populus simonii by chilling stress (4M-BM-0C, 10h).
We take the one year old plant for chilling stress (4M-BM-0C, 10h) and controls.Use the Affymetrix poplar gene chip to decrypt the gene functions and mechanisms in Populus simonii leaves. We used microarrays to detail the global programme of gene expression during chilling stress (4M-BM-0C, 10h). Po...
ORGANISM(S): Populus simonii 
2014-05-16 | E-GEOD-43872 | biostudies-arrayexpress
TranscriptomicsCombination of ABT-869 with SAHA on AML with FLT3-ITD
For the microarray experiments, MV4-11 and MOLM-14 cells were treated with DMSO control, ABT-869 3 nM, SAHA 6 M and combination therapy for 24 hours. Cells were then washed in PBS and high-quality total RNA was extracted RNeasy Midi Kit, according to the manufacturer’s instruction (Qiagen, Valencia...
ORGANISM(S): Homo sapiens 
2011-05-31 | E-GEOD-26114 | biostudies-arrayexpress
TranscriptomicsPACAP dependency of genes regulated in ischemia
We investigated the effects of PACAP treatment, and endogenous PACAP deficiency, on infarct volume, neurological function, and the cerebrocortical transcriptional response in a mouse model of stroke, middle cerebral artery occlusion (MCAO). PACAP-38 administered i.v. or i.c.v. one hour after MCAO si...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-5902 | biostudies-arrayexpress
UnknownImpact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial.
Not available
S-EPMC3731983 | biostudies-literature
TranscriptomicsCharacterization and comparison of two epidemic community-associated methicillin resistant Staphylococcus aureus clones of ST59 lineage
Comparing two subclones (Taiwan clone and Asian-Pacific clone) of CA-MRSA ST59. The Taiwan clone carries the Panton-Valentine leukocidin (PVL) genes, the staphylococcal chromosomal cassette mec (SCCmec) VT and is frequently isolated from patients with severe disease. The Asian-Pacific clone is PVL-n...
ORGANISM(S): Staphylococcus aureus 
2012-05-31 | E-MEXP-3627 | biostudies-arrayexpress
TranscriptomicsAutotoxicity mechanism of Oryza Sativa: Microarray analysis of rice plants in response to allelochemical ferulic acid
Autotoxicity plays an important mechanism in regulating plant productivity. Ferulic acid (FA) is phytotoxic and was identified in extracts and residues of rice plants as a candidate for rice allelochemicals. To help characterize the autotoxicity mechanism of rice, we present the first large-scale, t...
ORGANISM(S): Oryza sativa 
2013-07-22 | E-GEOD-34899 | biostudies-arrayexpress
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