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ProteomicsDiscovery of efficacy biomarkers for NSCLC with first-line anti-PD-1 immunotherapy by DIA
To discover potential plasma biomarkers, we are aiming to explore circulating and tumor-derived proteins related to the efficacy of anti-PD-1 treatment to select the optimal NSCLC patients for immunotherapy via DIA.
ORGANISM(S): Homo Sapiens 
2022-02-07 | PXD031474 |
ProteomicsFTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC
Older livers are more prone to hepatic ischaemia/reperfusion injury (HIRI), which severely limits their utilization in liver transplantation (LT); however, the potential mechanism remains unclear. Here, we demonstrated older livers exhibit a higher degree of ferroptosis during HIRI. Inhibiting ferro...
ORGANISM(S): Mus Musculus 
PXD051387 |
ProteomicsDeciphering aging-related changes based on cross-tissue proteomic profilling
The project aims to investigate the molecular mechanisms of aging by analyzing protein expression and modifications across various tissues in multiple organisms. Using advanced mass spectrometry, the project will collect and compare proteomic profiles from different organs at various ages. By identi...
ORGANISM(S): Mus Musculus 
2025-03-18 | PXD061948 |
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
PXD045174 |
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