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UnknownPrognostic Impact of Delirium in Older People With/Without Dementia: A Retrospective Cohort Study in Taiwan.

Objectives

To elucidate the hypothetically different interactions between delirium and post-discharge prognostic indicators in elderly hospital inpatients with versus without dementia.

Design

Retrospective cohort study of claims data by Taiwan National Health Insurance beneficiaries b...
S-EPMC12280676 | biostudies-literature
UnknownOpposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression.
Macrophages in a tumor microenvironment have been characterized as M1- and M2-polarized subtypes. Here, we discovered the different macrophages' impacts on lung cancer cell A549. The M2a/M2c subtypes promoted A549 invasion and xenograft tumor growth. The M1 subtype suppressed angiogenesis. M1 enhanc...
S-EPMC4585843 | biostudies-literature
UnknownLow-Density Lipoprotein Cholesterol and Mortality in Patients With Intracerebral Hemorrhage in Taiwan.
Objective: Lower serum low-density lipoprotein cholesterol (LDL-C) levels are associated with increased intracerebral hemorrhage (ICH) risk. However, reverse causality and residual confounding has not attracted public attention. Therefore, we assessed whether people with LDL-C have increased ...
S-EPMC8802633 | biostudies-literature
UnknownAI is a viable alternative to high throughput screening: a 318-target study.
High throughput screening (HTS) is routinely used to identify bioactive small molecules. This requires physical compounds, which limits coverage of accessible chemical space. Computational approaches combined with vast on-demand chemical libraries can access far greater chemical space, provided that...
S-EPMC10987645 | biostudies-literature
UnknownLiraglutide and Cardiovascular Outcomes in Type 2 Diabetes.

Background

The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown.

Methods

In this double-blind trial, we randomly assigned patients with type 2 diabetes and high cardiovascular risk t...
S-EPMC4985288 | biostudies-literature
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