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Correct anchoring of the mitotic spindle to the cell cortex is essential for proper cell division. However, how the architecture of the cell cortex is coordinately remodelled during mitotic progression remains poorly understood. Here, we show that depletion of EPLIN (an actin-bundling protein) cause...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD078855 | Pride

Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy approved. A major hurdle in NASH drug development is the poor translatability of preclinical studies to safe/effective clinical outcomes, and recent failures highlight a need to identify new targetable pathways. Dysr...

2023-04-13 | MTBLS5005 | MetaboLights
CLK1 plays a critical role in controlling energy expenditure through the CLK1-Thrap3-PPARγ axis.
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-08-16 | PXD027958 |
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