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ProteomicsGlobal lysine crotonylation profiling in the livers of mice
Crotonylation (Cr) is a novel post-transcriptional modification with the potential to regulate multiple biological processes. In order to improve the crotonylation dataset for further study, we performed LC-MS/MS with mouse liver samples to obtain the in vivo crotonylome. Totally, we identified 4607...
ORGANISM(S): Mus Musculus 
2020-01-19 | PXD015645 |
ProteomicsGlobal lysine crotonylation profiling of mouse liver (label-free quantitative proteomic data)
Crotonylation (Cr) is a novel post-translational modification with the potential to regulate multiple biological processes. To improve the crotonylation dataset for further study, we performed label-free LC-MS/MS with mouse liver samples to obtain an in vivo crotonylome. In this study, 11,408 croton...
ORGANISM(S): Mus Musculus 
2020-05-13 | PXD019145 |
UnknownClopidogrel Plus Aspirin vs Aspirin Alone in Patients With Acute Mild to Moderate Stroke: The ATAMIS Randomized Clinical Trial.

Importance

Dual antiplatelet therapy has been demonstrated to be superior to single antiplatelet in reducing recurrent stroke among patients with transient ischemic attack or minor stroke, but robust evidence for its effect in patients with mild to moderate ischemic stroke is lacking.

Obj...

S-EPMC10928538 | biostudies-literature
UnknownEfficacy and Safety of the RBD-Dimer-Based Covid-19 Vaccine ZF2001 in Adults.

Background

The ZF2001 vaccine, which contains a dimeric form of the receptor-binding domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an adjuvant, was shown to be safe, with an acceptable side-effect profile, and immunogenic in adults in phase 1 and 2 clini...
S-EPMC9127771 | biostudies-literature
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.

Purpose

Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in ad...
S-EPMC7880913 | biostudies-literature
UnknownA century of trends in adult human height.
Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in ad...
S-EPMC4961475 | biostudies-literature
UnknownWorldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants.

Background

Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic ...
S-EPMC5220163 | biostudies-literature
UnknownContributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.

Background

Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful cli...
S-EPMC6005056 | biostudies-literature
UnknownWorldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.

Background

Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to ...
S-EPMC5735219 | biostudies-literature
UnknownRising rural body-mass index is the main driver of the global obesity epidemic in adults.
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3-6. Here...
S-EPMC6784868 | biostudies-literature
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