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ProteomicsMulti-omics AnalysisIntegrated Proteomic and Metabolomic Analysis Reveals Underlying Host Responses in Pediatric Respiratory Syncytial Virus Pneumonia
Despite efforts made to reveal the underlying cause for differences in host responses and severity to Rrespiratory syncytial virus (RSV) infectionis an important pathogen causing pneumonia in children, few studies have used multi-omics data to investigate the pathogenies of RSV pneumonia. Here, meta...
ORGANISM(S): Homo Sapiens 
2023-02-14 | PXD040110 |
ProteomicsProteomic and metabolomic signatures associated with the immune response in healthy individuals immunized with an inactivated SARS-CoV-2 vaccine
CoronaVac (Sinovac), an inactivated vaccine for SARS-CoV-2, has been widely used for immunization. However, analysis of the underlying molecular mechanisms driving CoronaVac-induced immunity is still limited. Here, we applied a systems biology approach to understand the mechanisms behind the adaptiv...
ORGANISM(S): Homo Sapiens 
2022-03-09 | PXD032127 |
ProteomicsDependency of NELF-E-KAT2B epigenetic axis in breast cancer carcinogenesis
Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Here, we identified the transcriptional complex, NELF (Negative elongation factor), as an important regulator of this process. Using cancer cell lines and patient-derived tumor organoids, we demonstrated th...
ORGANISM(S): Homo Sapiens (human) 
2023-01-28 | PXD031304 | JPOST Repository
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