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ProteomicsPhospho-proteomic Analyses Provide Insight into Underlying Molecular Mechanisms of NETosis
NETosis, a novel cell death leads to neutrophil extracellular trap (NET) formation, is involved in both infectious and noninfectious disease. However, mechanisms underlying NETosis remain unclear. To explore the underlying molecular mechanisms and common factors associated with both NOX-dependent an...
ORGANISM(S): Homo Sapiens 
2019-06-27 | PXD014418 |
ProteomicsComparative proteomic analyses of the liver in D-galactosamine sensitized mice treated with different toll-like receptor agonists
Acute liver failure (ALF) is a severe consequence of abrupt hepatocyte injury with lethal outcomes. Three toll-like receptor (TLR) agonists, including polyinosinic-polycytidylic acid [poly(I:C)], lipopolysaccharide (LPS), and cytosine-phosphate-guanine oligonucleotide (CpG ODN), respectively, cause ...
ORGANISM(S): Mus Musculus 
2020-01-19 | PXD017180 |
MetabolomicsAcupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending MM patient survival. However, most patients a...
2022-02-21 | MTBLS3487 | MetaboLights
TranscriptomicsDigital gene expression analysis reveals genes associated with hexythiazox resistance in citrus red mite, Panonychus citri
We compared a miticides resistant strain and a susceptible strain's gene expression profile to reveal genes associated with miticide resistance in Panonychus citri.
ORGANISM(S): Panonychus citri 
2013-06-11 | E-MTAB-1193 | biostudies-arrayexpress
ProteomicsCIMAGE2.0: An Expanded Tool for Quantitative Analysis of Activity-based Probe Profiling (ABPP) Data
Activity-based Protein Profiling (ABPP) is a powerful chemo-proteomic method to study proteins’ activity, modifications and interactions in a high-throughput manner. In ABPP experiments, accurate quantification is crucial to determine the extent of probe labeling at the level of either target protei...
ORGANISM(S): Homo Sapiens 
2021-03-16 | PXD024754 |
ProteomicsSFXN2 adjusts cell proliferation in multiple myeloma
SFXN2 adjusts cell proliferation in multiple myeloma
ORGANISM(S): Homo Sapiens 
PXD027607 |
TranscriptomicsTranscriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2010]
Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases:  A Report From the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Gen...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-35202 | biostudies-arrayexpress
TranscriptomicsTranscriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2007]
Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases:  A Report From the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Gen...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-35201 | biostudies-arrayexpress
GenomicsWhole Genome Sequencing of Pediatric Acute Megakaryoblastic Leukemia

We have performed whole genome sequencing of 4 cases of pediatric acute megakaryoblastic leukemia to identify somatic genetic alterations driving leukemogenesis.

phs000413.v1.p1 | EGA
GenomicsPCGP Ph-likeALL RNASeq - samples
DATA FILES FOR SJPhLike-RNASeq
EGAD00001001016 | EGA
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