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TranscriptomicsSpatial and Temporal Regulation of Gene Expression in the Mammalian Growth Plate
To explore the mechanisms responsible for spatial and temporal regulation of the growth plate, we microdissected postnatal rat growth plates into their constituent zones and then used microarray analysis to characterize the changes in gene expression that occur as chondrocytes undergo spatially-asso...
ORGANISM(S): Rattus norvegicus 
2010-02-22 | E-GEOD-16981 | biostudies-arrayexpress
MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
TranscriptomicsBroad shifts in gene expression during early postnatal life are associated with shifts in histone methylation patterns
During early postnatal life, extensive changes in gene expression occur concomitantly in multiple major organs, indicating the existence of a common core developmental genetic program. This program includes hundreds of growth-promoting genes that are downregulated with age in liver, kidney, lung, an...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-49785 | biostudies-arrayexpress
UnknownWhich Sudden Stratospheric Warming Events Are Most Predictable?
Not available
S-EPMC9540765 | biostudies-literature
TranscriptomicsTemporal changes of gene expression in rat kidney and lung, and the effect of prior growth inhibition on these changes
Temporal changes of gene expression from 1-wk- to 5-wk-old rat in kidney and lung, and the effect of prior growth inhibition on these genetic changes. In mammals, body growth is rapid in early life but decelerates with age. Somatic growth deceleration is caused by a gradual decline in cell prolifera...
ORGANISM(S): Rattus norvegicus 
2010-09-16 | E-GEOD-16792 | biostudies-arrayexpress
TranscriptomicsLung transcript expression profile after Gata5 gene deletion
Gata5 is a zinc finger transcription factor that is expressed in embryonic pulmonary mesenchyme and becomes upregulated in the lungs, gut, and bladder during postnatal development. We used microarray to comapre gene expression profiles of mouse lung between Gata5 knockout and wild type mice. We hope...
ORGANISM(S): Mus musculus 
2013-08-26 | E-GEOD-47425 | biostudies-arrayexpress
MetabolomicsMetabolomics Analysis Reveals Tissue-Specific Metabolite Compositions in Leaf Blade and Traps of Carnivorous Nepenthes Plants
Nepenthes is a genus of carnivorous plants that evolved a pitfall trap, the pitcher, to catch and digest insect prey to obtain additional nutrients. Each pitcher is part of the whole leaf, together with a leaf blade. These two completely different parts of the same organ were studied separately in a...
2020-07-10 | MTBLS1783 | MetaboLights
UnknownThe Effect of Y Addition on Oxidation Resistance of Bulk W-Cr Alloys.
Not available
S-EPMC11642325 | biostudies-literature
UnknownDepression Classification Using Frequent Subgraph Mining Based on Pattern Growth of Frequent Edge in Functional Magnetic Resonance Imaging Uncertain Network.
Not available
S-EPMC9106560 | biostudies-literature
TranscriptomicsEvidence that variation in adult body size among mammalian species is achieved by modulating the pace of a growth-regulating genetic program
Body size varies enormously among mammalian species. In small mammals, body growth is typically suppressed rapidly, within weeks, whereas in large mammals, growth is suppressed slowly, over years, allowing for a greater adult size. We recently reported evidence that body growth suppression in rodent...
ORGANISM(S): Ovis aries 
2014-05-19 | E-GEOD-48916 | biostudies-arrayexpress
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