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Title: Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity Abstract: Evidence is emerging that the PGC-1 coactivators serve a critical role in skeletal muscle metabolism, function, and disease. Mice with total PGC-1 defic...
ORGANISM(S): Mus musculus 
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (e...
ORGANISM(S): Mus musculus 
2012-06-21 | GSE36284 | GEO
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
Proteomic data from technical developments of a nanowell-mediated two-dimensional (2D) reversed-phase nanoflow liquid chromatography (LC) separation for in-depth proteome profiling of low-nanogram samples.
ORGANISM(S): Homo sapiens (Human) 
2018-10-18 | PXD010150 | Pride
The microtubule (MT) cytoskeleton can provide a mechanical resistance that can impede the motion of contracting cardiomyocytes. Yet a role of the MT network in human heart failure is unexplored. Here we utilize mass spectrometry to characterize changes to the cytoskeleton in human heart failure. P...
ORGANISM(S): Homo sapiens (Human) 
2018-06-06 | PXD008934 | Pride
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