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TranscriptomicsDefective K-Ras Oncoproteins Initiate Cancer In Vivo and Evolve to Overcome Impaired Effector Binding
The oncogenic proteins expressed in human cancer cells are exceedingly difficult targets for drug discovery due to intrinsic properties of the Ras GTPase switch. As a result, recent efforts have largely focused on inhibiting Ras-regulated kinase effector cascades, particularly the Raf/MEK/ERK and PI...
ORGANISM(S): Mus musculus 
2011-09-30 | E-GEOD-28687 | biostudies-arrayexpress
TranscriptomicsGene expression of genetically related and unrelated human embryonic stem cell lines
Gene expression of sibling human ES cell lines are more similar to each other than unrelated cell lines. Undifferentiated human embryonic stem cells were used for analysis. We sought to determine whether genetic differences underly variations between different human ES cell lines. Sibling cell lines...
ORGANISM(S): Homo sapiens 
2009-03-19 | E-GEOD-15294 | biostudies-arrayexpress
UnknownRedistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.
Not available
S-EPMC4268254 | biostudies-literature
UnknownIndividual prediction of heart failure among childhood cancer survivors.
Not available
S-EPMC4314592 | biostudies-literature
GenomicsmodENCODE_White Lab: genome-wide ChIP data of KW3-Pcl-D2 from D.sim_WPP on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor KW3-Pcl-D2 from D.sim_WPP generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms an...
ORGANISM(S): Drosophila simulans 
2011-02-15 | E-GEOD-25662 | biostudies-arrayexpress
GenomicsmodENCODE_White Lab: genome-wide ChIP data of H3K27me3 from D.sim_WPP on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor H3K27me3 from D.sim_WPP generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms and ...
ORGANISM(S): Drosophila simulans 
2011-02-15 | E-GEOD-25663 | biostudies-arrayexpress
GenomicsmodENCODE_White Lab: genome-wide ChIP data of H3K27me3 from D.sim_E0-4h on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor H3K27me3 from D.sim_E0-4h generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms an...
ORGANISM(S): Drosophila simulans 
2011-02-15 | E-GEOD-25664 | biostudies-arrayexpress
GenomicsmodENCODE_White Lab: genome-wide ChIP data of KW3-Trl-D2 from D.pse_E0-4h on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor KW3-Trl-D2 from D.pse_E0-4h generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms ...
ORGANISM(S): Drosophila pseudoobscura 
2011-02-15 | E-GEOD-25667 | biostudies-arrayexpress
GenomicsmodENCODE_White Lab: genome-wide ChIP data of KW3-Psq-D2 from D.pse_E0-4h on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor KW3-Psq-D2 from D.pse_E0-4h generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms ...
ORGANISM(S): Drosophila pseudoobscura 
2011-02-15 | E-GEOD-25666 | biostudies-arrayexpress
GenomicsmodENCODE_White Lab: genome-wide ChIP data of H3K27me3 from D.pse_WPP on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor H3K27me3 from D.pse_WPP generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms and ...
ORGANISM(S): Drosophila pseudoobscura 
2011-02-15 | E-GEOD-25668 | biostudies-arrayexpress
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