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MetabolomicsVegetable Signatures Derived from Human Urinary Metabolomic Data in Controlled Feeding Studies
Examination of changes in urinary metabolomic profiles after vegetable ingestion may lead to new methods of assessing plant food intake. To this regard, we developed a proof-of-principle methodology to identify urinary metabolomic signatures for spinach, celery, and onion. Three feeding studies were...
2019-05-30 | MTBLS683 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
TranscriptomicsGenome-wide characterization of long nonpolyadenylated RNAs, experiment II
We have used deep sequencing to explore the repertoire of both poly(A)+ and poly(A)- RNAs from two standard cell lines, HeLa cells and human embryonic stem cell (hESC) H9 cells. Examination of nonpolyadenylated and polyadenylated in 2 cell types.
ORGANISM(S): Homo sapiens 
2011-01-28 | E-GEOD-24399 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of RNAs associated with Lin28
We used immunoprecipitation to pulldown Lin28 associated RNA targets and used genome-wide high throughput deep sequencing to identified those Lin28-associated RNAs. Keywords: Lin28 IP-RNAseq Examination of Lin28 immunoprecipitated RNA transcripts
ORGANISM(S): Homo sapiens 
2011-01-18 | E-GEOD-23109 | biostudies-arrayexpress
TranscriptomicsGenome-wide characterization of long nonpolyadenylated RNAs
We have used deep sequencing to explore the repertoire of both poly(A)+ and poly(A)- RNAs from two standard cell lines, HeLa cells and human embryonic stem cell (hESC) H9 cells. Examination of nonpolyadenylated and polyadenylated RNA in 2 cell types.
ORGANISM(S): Homo sapiens 
2012-06-30 | E-GEOD-22666 | biostudies-arrayexpress
TranscriptomicsComparative analysis of human and mouse transcriptomes of Th17 cell priming.
Uncontrolled Th17 cell activity is associated with cancer and autoimmune and inflammatory diseases. To validate the potential relevance of mouse models of targeting the Th17 pathway in human diseases we used RNA sequencing to compare the expression of coding and non-coding transcripts during the pri...
ORGANISM(S): Homo sapiens 
2016-04-07 | E-GEOD-52260 | biostudies-arrayexpress
MetabolomicsHepatic Metabolomics Investigation in Acute and Chronic Murine Toxoplasmosis
Toxoplasma gondii poses a great threat to human health, with no approved vaccine available for the treatment of T. gondii infection. T. gondii infections are not limited to the brain, and may also affect other organs especially the liver. Identification of host liver molecules or pathways involved i...
2019-08-06 | MTBLS586 | MetaboLights
TranscriptomicsStranded RNA-seq of H9 cells
We have used stranded RNA-seq to explore RNA editing in H9 cells Examination RNA editing with stranded RNA-seq
ORGANISM(S): Homo sapiens 
2013-02-22 | E-GEOD-44450 | biostudies-arrayexpress
MetabolomicsA longitudinal ¹H NMR-based urinary metabolomics dataset in a birth cohort for childhood atopic diseases

This dataset presents longitudinal urinary metabolomic profiles from 198 children at 1 month, 6 months, 1 year, 3 years and 5 years. It includes demographic data, feeding practices, parental atopy, household income and atopic disease status over time. Total and allergen-specific IgE (mite, egg, c...

2025-07-28 | MTBLS12785 | MetaboLights
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