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TranscriptomicsSmall RNA expression and caste differentiation in the honeybee
Honeybees are very important eusocial insects and are involved in the pollination of many plants. Queen bees and worker bees develop from the same fertilized eggs, and are thus genetically identical despite their substantial behavioural and physiological differences. The mechanism governing developm...
ORGANISM(S): Apis mellifera 
2014-07-28 | E-GEOD-52630 | biostudies-arrayexpress
TranscriptomicsMapping the C. elegans non-coding transcriptome with a whole genome tiling microarray
The number of annotated protein coding genes in the genome of Caenorhabditis elegans is similar to that of other animals, but the extent of its non-protein coding transcriptome remains unknown. Expression profiling on whole genome tiling microarrays applied to a mixed stage C. elegans population ver...
ORGANISM(S): Caenorhabditis elegans 
2007-09-06 | E-GEOD-8543 | biostudies-arrayexpress
TranscriptomicsFeeding with miR-184 affects the mRNA expression profile of queen larvae
By comparing mRNA profiles of the two groups of bee larvae (treated by miR-184 and water), we found that there were 279 mRNAs which were differently expressed between treated and control larvae (ratio>2 and p<0.01), of which 200 mRNAs were down-regulated in treated larvae, and 79 mRNAs were down-reg...
ORGANISM(S): Apis mellifera 
2014-01-06 | E-GEOD-44911 | biostudies-arrayexpress
TranscriptomicsDevelopment of a versatile, target-oriented tiling microarray assay for measuring allele-specific gene expression
In the study of gene expression regulation in plants, it is often desirable to distinguish transcript pools derived from different alleles present in the same organism. We report here an oligonucleotide tiling microarray designed to specifically target 518 single nucleotide polymorphisms (SNPs) betw...
ORGANISM(S): Oryza sativa 
2010-07-01 | E-GEOD-20678 | biostudies-arrayexpress
TranscriptomicsRecipe for a busy bee: MicroRNAs in honey bee caste determination
Social caste determination in the honey bee is assumed to be determined by the dietary status of the young larvae and translated into physiological and epigenetic changes through nutrient-sensing pathways. We have employed Illumina/Solexa sequencing to examine the small RNA content in the bee larval...
ORGANISM(S): Apis mellifera 
2014-01-06 | E-GEOD-44853 | biostudies-arrayexpress
TranscriptomicsMIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes
The piRNA machinery is known for its role in mediating epigenetic silencing of transposons. Recent studies suggest that this function also involves piRNA-guided cleavage of transposon-derived transcripts. As many piRNAs also appear to have the capacity to target diverse mRNAs, this raises the intrig...
ORGANISM(S): Mus musculus 
2015-04-09 | E-GEOD-67683 | biostudies-arrayexpress
TranscriptomicsLncRNA profile study during Human MSC adipogenic differentiation: Day0 vs Day3 vs Day6
LncRNA transcriptional profiling of human mesenchymal stem cells comparing control undifferentiated HMSC with Day3 and Day6 adipogenic differentiation stages Three-condition experiment, Day0 vs. Day3 vs Day6 cells. Day0: 4 replicates, Day3: 3 replicates and Day6: 3 replicates.
ORGANISM(S): Homo sapiens 
2014-05-22 | E-GEOD-57593 | biostudies-arrayexpress
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081738 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Kinobeads
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081735 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CPTAC Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081739 | MassIVE
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