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ProteomicsCharacterization of the acetylome associated with rapamycin-induced autophagy in HeLa cells
Autophagy is a lysosomal-mediated catabolic process that degrades cytoplasmic components to help maintain cellular homeostasis and cell survival during exposure to stress. Lysine acetylation is a reversible post-translational modification that plays an important role in the regulation of diverse cel...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD005793 | Pride
Autophagy  rapamycin  acetylome  acetylation  acetyltransferase 
ProteomicsPhosphoproteome analysis reveals the importance of Greatwall-endosulfine pathway to regulate cell-cycle progression upon the rapamycin-induced autophagy
Protein phosphorylation plays an important role in the process of autophagy. Autophagy is associated with cell cycle, which is controlled by the balance between the cyclin-dependent kinases and phosphatases activities. However, up to now, the signal transduction pathways that underlied rapamycin-ind...
ORGANISM(S): Homo sapiens (Human) 
2021-04-06 | PXD014737 | Pride
Autophagy  phosphoproteome  rapamycin  cell cycle  cdk1 
Genomicsena-DATASET-BGI-26-11-2015-07:58:13:440-13 - samples
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAD00001001691 | EGA
GenomicsWhole-genome sequencing in 14 cases and whole-exome sequencing in 90 cases of Chinese ESCC
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAS00001001487 | EGA
ProteomicsPrecipitation mediates the role of stochastic process in soil microbial community assembly
Precipitation change is often associated with climate warming, but its effects on soil microbial community assembly remain relatively underexplored. Traditionally, it is thought that increasing the magnitude of environmental changes will increase the importance of deterministic processes in communit...
ORGANISM(S): Uncultivated Soil Bacterium 
2020-12-13 | PXD023103 |
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